Increasing Prevalence of Untypable and Mixed Genotypes of Hepatitis C Virus in Pakistan: Latest Trends in 2018

被引：3
作者：
Wahid, Braira [1 ]
Naeem, Nabiha [1 ]
Altaf, Saba [1 ]
Ilyas, Nimra [1 ]
机构：
[1] Univ Management & Technol, Sch Sci, Dept Life Sci, Lahore 54000, Pakistan
来源：
VIRAL IMMUNOLOGY | 2019年 / 32卷 / 04期
关键词：
Genome Centre for Molecular Based Diagnostics and Research (GCMBDR); Pakistan; HCV; genotyping; THERAPY;
D O I：
10.1089/vim.2018.0152
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Hepatitis C virus (HCV) genotyping is a critical parameter that acts as predictor of treatment response. According to previously reported findings, about 11 million population of Pakistan are HCV infected. Accumulating data suggest that genotype is the most prevalent genotype and mixed and untypable genotypes are the least prevalent genotypes of HCV. We observed that overall prevalence of mixed genotype (5.03%) and untypable genotype (3.3%) of HCV is on constant rise. This study highlights that the emergence of novel quasispecies could be reason of treatment failure in patients receiving direct-acting antiviral drugs.
引用
收藏
页码：192 / 194
页数：3
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