Cyr61/CCN1 affects the integrin-mediated migration of prostate cancer cells (PC-3) in vitro

被引:14
|
作者
Schmitz, Patrick [1 ]
Gerber, Ursula [1 ]
Juengel, Eva [2 ]
Schuetze, Norbert [3 ]
Blaheta, Roman [2 ]
Bendas, Gerd [1 ]
机构
[1] Univ Bonn, Dept Pharm, D-53121 Bonn, Germany
[2] Frankfurt Univ Hosp, Ctr Surg, Res Lab, Frankfurt, Germany
[3] Univ Wurzburg, Orthoped Ctr Musculoskeletal Res, D-97070 Wurzburg, Germany
关键词
CCN/Cyr61; migration; prostate cancer cells (PC-3); integrins; fibronectin; collagen; ECM;
D O I
10.5414/CPP51047
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
[No abstract available]
引用
收藏
页码:47 / 50
页数:4
相关论文
共 29 条
  • [21] Smilax glabra Roxb. Inhibits Collagen Induced Adhesion and Migration of PC3 and LNCaP Prostate Cancer Cells through the Inhibition of Beta 1 Integrin Expression
    Kwon, Oh Yun
    Ryu, Sujin
    Choi, Jong Kyu
    Lee, Seung Ho
    MOLECULES, 2020, 25 (13):
  • [22] Effect of laminin tyrosine-isoleucine-glycine-serine-arginine peptide on the growth of human prostate cancer (PC-3) cells in vitro
    Yu, Hai-ning
    Zhang, Lan-cui
    Yang, Jun-guo
    Das, Undurti N.
    Shen, Sheng-rong
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2009, 616 (1-3) : 251 - 255
  • [23] Imipramine Inhibits Migration and Invasion in Metastatic Castration-Resistant Prostate Cancer PC-3 Cells via AKT-Mediated NF-κB Signaling Pathway
    Lim, Eun Yeong
    Park, Joon
    Kim, Yun Tai
    Kim, Min Jung
    MOLECULES, 2020, 25 (20):
  • [24] Rac1-Dependent Lamellipodial Motility in Prostate Cancer PC-3 Cells Revealed by Optogenetic Control of Rac1 Activity
    Kato, Takuma
    Kawai, Katsuhisa
    Egami, Youhei
    Kakehi, Yoshiyuki
    Araki, Nobukazu
    PLOS ONE, 2014, 9 (05):
  • [25] The miRNA let-7a1 inhibits the expression of insulin-like growth factor 1 receptor (IGF1R) in prostate cancer PC-3 cells
    Wang, Li-Na
    Chen, Wei-Wen
    Zhang, Ju
    Li, Chao-Yang
    Liu, Chun-Yan
    Xue, Jing
    Zhang, Peng-Ju
    Jiang, An-Li
    ASIAN JOURNAL OF ANDROLOGY, 2013, 15 (06) : 753 - 758
  • [26] SPARC Induces E-Cadherin Repression and Enhances Cell Migration through Integrin αvβ3 and the Transcription Factor ZEB1 in Prostate Cancer Cells
    Lopez-Moncada, Fernanda
    Jose Torres, Maria
    Lavanderos, Boris
    Cerda, Oscar
    Castellon, Enrique A.
    Contreras, Hector R.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (11)
  • [27] Normal Basal Epithelial Cells Stimulate the Migration and Invasion of Prostate Cancer Cell RM-1 by TGF-β1/STAT3 Axis in vitro
    Li, Chun-Yan
    Chen, Chun-Ya
    An, Jian-Hong
    Wu, Jian-Bin
    Shen, Hong
    CANCER MANAGEMENT AND RESEARCH, 2021, 13 : 3685 - 3697
  • [28] Enhanced Sensitivity to Sunitinib by Inhibition of Akt1 Expression in Human Castration-resistant Prostate Cancer PC3 Cells Both In Vitro and In Vivo
    Nishikawa, Masatomo
    Miyake, Hideaki
    Fujisawa, Masato
    UROLOGY, 2015, 85 (05) : 1215.e1 - 1215.e7
  • [29] Ets-1 is implicated in the regulation of androgen co-regulator FHL2 and reveals specificity for migration, but not invasion, of PC3 prostate cancer cells
    Shaikhibrahim, Zaki
    Langer, Berit
    Lindstrot, Andreas
    Florin, Alexandra
    Bosserhoff, Anja
    Buettner, Reinhard
    Wernert, Nicolas
    ONCOLOGY REPORTS, 2011, 25 (04) : 1125 - 1129