Discovery of a novel orexigenic neuropeptide, 26RFa

被引：0

作者：

Chartrel, Nicolas ^{[1
]}

Jeandel, Lydie ^{[1
]}

Alexandre, David ^{[1
]}

机构：

[1] Univ Rouen, INSERM, U982, IRIB, F-76821 Mont St Aignan, France

来源：

CORRESPONDANCES EN METABOLISMES HORMONES DIABETES ET NUTRITION | 2013年 / 17卷 / 03期

关键词：

Deorphanization; Neuropeptide; Hypothalamus; Feeding behaviour; Anorexia nervosa; HYPOTHALAMIC NEUROPEPTIDE; PEPTIDE; RECEPTOR; IDENTIFICATION; LIGAND; FAMILY; MICE;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

26RFa is a novel neuropeptide identified as the endogenous ligand of the human orphan receptor GPR103. 26RFa and GPR103 are localized in hypothalamic nuclei regulating feeding behaviour. 26RFa stimulates appetite. The 26RFa system is up-regulated in obese patients and adolescents suffering of anorexia nervosa.

引用

页码：66 / 69

页数：4

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