Glycopeptide resistance in enterococci

被引:301
作者
Arthur, M [1 ]
Reynolds, P [1 ]
Courvalin, P [1 ]
机构
[1] UNIV CAMBRIDGE,DEPT BIOCHEM,CAMBRIDGE CB2 1QW,ENGLAND
关键词
D O I
10.1016/0966-842X(96)10063-9
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Glycopeptide resistance in enterococci results from the production of peptidoglycan precursors with low affinity for these antibiotics. The mobility of the resistance genes by transposition and conjugation and the ability of the resistance proteins to interfere with synthesis of normal precursors in different hosts indicate that dissemination into other bacterial species should be anticipated.
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页码:401 / 407
页数:7
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