Prognosis of mature T cell lymphoma is poorer than that of diffuse large B cell lymphoma in IPI low-risk group, but not in intermediate- and high-risk groups

被引:5
作者
Kihara, Rika [1 ,2 ]
Watanabe, Tomoyuki [1 ,3 ]
Yano, Takahiro [1 ,4 ]
Uike, Naokuni [1 ,5 ]
Okamura, Seiichi [1 ,6 ]
Kawano, Fumio [1 ,7 ]
Hanada, Shuichi [1 ,8 ]
Sunami, Kazutaka [1 ,9 ]
Inoue, Nobumasa [1 ,10 ]
Sawamura, Morio [1 ,11 ]
Yoshida, Shin-ichiro [1 ,12 ]
Shimomura, Takeshi [1 ,13 ]
Kitano, Kiyoshi [1 ,14 ]
Kojima, Yuki [1 ,2 ]
Horibe, Keizo [1 ,2 ]
Nagai, Hirokazu [1 ,2 ]
机构
[1] Natl Hosp Org, Clin Hematol Grp, Nagoya, Aichi, Japan
[2] Natl Hosp Org, Nagoya Med Ctr, Clin Res Ctr, Naka Ku, Nagoya, Aichi 4600001, Japan
[3] Aichi Gakuin Univ, Fac Psychol & Phys Sci, Nisshin, Japan
[4] Natl Hosp Org, Tokyo Med Ctr, Tokyo, Japan
[5] Natl Hosp Org, Kyushu Canc Ctr, Fukuoka, Japan
[6] Natl Hosp Org, Kyushu Med Ctr, Fukuoka, Japan
[7] Natl Hosp Org, Kumamoto Med Ctr, Kumamoto, Japan
[8] Natl Hosp Org, Kagoshima Med Ctr, Kagoshima, Japan
[9] Natl Hosp Org, Okayama Med Ctr, Okayama, Japan
[10] Natl Hosp Org, Osaka Med Ctr, Osaka, Japan
[11] Natl Hosp Org, Nishigunma Natl Hosp, Shibukawa, Japan
[12] Natl Hosp Org, Nagasaki Med Ctr, Nagasaki, Japan
[13] Natl Hosp Org, Hiroshima Nishi Med Ctr, Otake, Japan
[14] Natl Hosp Org, Matsumoto Med Ctr, Matsumoto, Nagano, Japan
关键词
Mature T cell lymphoma; IPI; DLBCL; NON-HODGKINS-LYMPHOMA;
D O I
10.1007/s12185-012-1243-2
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Mature T cell lymphoma has been noted for poor prognosis when compared with B cell lymphoma, even in the pre-rituximab era. To confirm this difference, a retrospective cohort study was conducted. One hundred-and nineteen patients with mature T cell lymphoma and 568 patients with diffuse large B cell lymphoma (DLBCL) who did not receive rituximab as first induction were studied. Overall survival (OS) was worse for patients with international prognostic index (IPI) scores indicating low-risk mature T cell lymphoma than for those with DLBCL (3-year OS 87 % vs. 58 %, P = 0.001), but not in other risk groups. Prognosis of mature T cell lymphoma was significantly poorer in the IPI low-risk group, as compared with DLBCL.
引用
收藏
页码:98 / 102
页数:5
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