Efficient iridium-catalyzed C-H functionalization/silylation of heteroarenes

被引：153

作者：

Lu, Biao

Falck, John R. ^{[1
]}

机构：

[1] Univ Texas SW Med Ctr Dallas, Dept Biochem, Dallas, TX 75390 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 39期

关键词：

C-H activation; heterocycles; iridium; silanes;

D O I：

10.1002/anie.200802456

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

CSi investigation: The efficient iridium-catalyzed C-H functionalization/ silylation of a wide variety of N-, S-, and O-heteroarenes, including N-unsubstituted indoles, is promoted by 2-norbornene and features a high level of regioselectivity (see scheme; Ts = p-toluenesulfonyl, cod = cyclooctadiene). (Chemical Equation Presented) © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

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页码：7508 / 7510

页数：3

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