Testing of efficacy of photodynamic therapy with a new photosensitizer - a of chlorin e6 derivative (BLC 1010)

被引：0

作者：

Stranadko, EP ^{[1
]}

Riabov, MV ^{[1
]}

Volkova, NN ^{[1
]}

Spaniol, S ^{[1
]}

Rauschning, W ^{[1
]}

Nifantiev, NE ^{[1
]}

机构：

[1] State Res Ctr Laser Med, Moscow 121165, Russia

来源：

LASER-TISSUE INTERACTIONS, THERAPEUTIC APPLICATIONS, AND PHOTODYNAMIC THERAPY | 2001年 / 4433卷

关键词：

photodynamic therapy; new chlorin e6 derivative; phototoxicity; diode lasers;

D O I：

10.1117/12.446519

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Efficacy of PDT with new chlorin e6 photosensitizer (BLC 1010) has been tested in 72 cancer patients. 44 patients (61 %) achieved a complete response and 39 % of the patients a partial response (28 patients, including 15 patients treated for palliation). Rapid elimination of BLC 1010 from the organism solves the problem of skin phototoxicity encountered in PDT up to now. This property together with its high tumor to normal ratio makes it a promising photosensitizer for PDT. Further advantage is that portable diode lasers with proper wavelength are available.

引用

页码：155 / 157

页数：3

共 5 条

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