Space Flight Calcium: Implications for Astronaut Health, Spacecraft Operations, and Earth

被引:57
作者
Smith, Scott M. [1 ]
McCoy, Torin [1 ]
Gazda, Daniel [2 ]
Morgan, Jennifer L. L. [3 ]
Heer, Martina [4 ,5 ]
Zwart, Sara R. [6 ]
机构
[1] NASA, Human Hlth & Performance Directorate, Lyndon B Johnson Space Ctr, Houston, TX 77058 USA
[2] Wyle Sci Technol & Engn Grp, Houston, TX 77058 USA
[3] Oak Ridge Associated Univ, Oak Ridge, TN 37831 USA
[4] Profil Inst Stoffwechselforsch GmbH, D-41460 Neuss, Germany
[5] Univ Bonn, D-53115 Bonn, Germany
[6] Univ Space Res Assoc, Div Space Life Sci, Houston, TX 77058 USA
关键词
bed rest; bone; calcium; collagen crosslinks; dual-energy X-ray absorptiometry; space flight; INDUCED BONE LOSS; RENAL STONE RISK; BODY NEGATIVE-PRESSURE; RESISTIVE VIBRATION EXERCISE; LONG-DURATION SPACEFLIGHT; PROLONGED BED REST; ACID-BASE-BALANCE; TREADMILL EXERCISE; URINARY CALCIUM; RESISTANCE EXERCISE;
D O I
10.3390/nu4122047
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
The space flight environment is known to induce bone loss and, subsequently, calcium loss. The longer the mission, generally the more bone and calcium are lost. This review provides a history of bone and calcium studies related to space flight and highlights issues related to calcium excretion that the space program must consider so that urine can be recycled. It also discusses a novel technique using natural stable isotopes of calcium that will be helpful in the future to determine calcium and bone balance during space flight.
引用
收藏
页码:2047 / 2068
页数:22
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