The use of gold nanoparticle aggregation for DNA computing and logic-based biomolecular detection

被引：0

作者：

Lee, In-Hee ^{[1
]}

Yang, Kyung-Ae ^{[1
,2
]}

Lee, Ji-Hoon ^{[2
]}

Park, Ji-Yoon ^{[3
]}

Chai, Young Gyu ^{[3
]}

Lee, Jae-Hoon ^{[4
]}

Zhang, Byoung-Tak ^{[1
,2
]}

机构：

[1] Seoul Natl Univ, Sch Engn & Comp Sci, Seoul 151742, South Korea

[2] Seoul Natl Univ, Ctr Bioinformat Technol, Seoul 151742, South Korea

[3] Hanyang Univ, Div Mol & Life Sci, Ansan 426791, Gyeonggi Do, South Korea

[4] Tech Univ Berlin, Fachgebiet Mikrobiol & Genet, Inst Biotechnol, D-13355 Berlin, Germany

来源：

NANOTECHNOLOGY | 2008年 / 19卷 / 39期

关键词：

D O I：

10.1088/0957-4484/19/39/95103

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

The use of DNA molecules as a physical computational material has attracted much interest, especially in the area of DNA computing. DNAs are also useful for logical control and analysis of biological systems if efficient visualization methods are available. Here we present a quick and simple visualization technique that displays the results of the DNA computing process based on a colorimetric change induced by gold nanoparticle aggregation, and we apply it to the logic-based detection of biomolecules. Our results demonstrate its effectiveness in both DNA-based logical computation and logic-based biomolecular detection.

引用

页数：6

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