Lipin-1 restrains Lipid synthesis to promote proresolving macrophage function and disease resolution

被引:0
|
作者
Bamgbose, Temitayo Taiwo
Schilke, Robert M.
Blackburn, Cassidy M. R.
Woolard, Matthew D.
机构
来源
JOURNAL OF IMMUNOLOGY | 2022年 / 208卷 / 01期
关键词
D O I
10.4049/jimmunol.208.Supp.54.23
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
54.23
引用
收藏
页数:2
相关论文
共 50 条
  • [31] Exendin-4 improves ER stress-induced lipid accumulation and regulates lipin-1 signaling in HepG2 cells
    Lee, Jinmi
    Hong, Seok-Woo
    Kwon, Hyemi
    Park, Se Eun
    Rhee, Eun-Jung
    Park, Cheol-Young
    Oh, Ki-Won
    Park, Sung-Woo
    Lee, Won-Young
    CELL STRESS & CHAPERONES, 2018, 23 (04): : 629 - 638
  • [32] Lipin-1 transcriptional co-regulatory activity enhances anti-inflammatory responses in lipid-loaded macrophages and induces atheroprotection
    Blackburn, Cassidy
    Schilke, Robert M.
    Vozenilek, Aimee E.
    Finck, Brian N.
    Woolard, Matthew D.
    JOURNAL OF IMMUNOLOGY, 2020, 204 (01):
  • [33] Lipin-1 regulation of phospholipid synthesis maintains endoplasmic reticulum homeostasis and is critical for triple-negative breast cancer cell survival
    He, Jingquan
    Zhang, Feng
    Tay, Li Wei Rachel
    Boroda, Salome
    Nian, Weiqi
    Levental, Kandice R.
    Levental, Ilya
    Harris, Thurl E.
    Chang, Jeffrey T.
    Du, Guangwei
    FASEB JOURNAL, 2017, 31 (07): : 2893 - 2904
  • [34] Lipin-1 Phosphatidic Phosphatase Activity Modulates Phosphatidate Levels to Promote Peroxisome Proliferator-activated Receptor γ (PPAR γ) Gene Expression during Adipogenesis
    Zhang, Peixiang
    Takeuchi, Kazuharu
    Csaki, Lauren S.
    Reue, Karen
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 287 (05) : 3485 - 3494
  • [35] Annexin A1 and specialized proresolving lipid mediators: promoting resolution as a therapeutic strategy in human inflammatory diseases
    Perucci, Luiza Oliveira
    Sugimoto, Michelle Amantea
    Gomes, Karina Braga
    Dusse, Luci Maria
    Teixeira, Mauro Martins
    Sousa, Lirlandia Pires
    EXPERT OPINION ON THERAPEUTIC TARGETS, 2017, 21 (09) : 879 - 896
  • [36] Stereoselective synthesis of protectin D1: a potent anti-inflammatory and proresolving lipid mediator
    Aursnes, M.
    Tungen, J. E.
    Vik, A.
    Dalli, J.
    Hansen, T. V.
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2014, 12 (03) : 432 - 437
  • [37] HMGB1-C1q complexes regulate macrophage function by switching between leukotriene and specialized proresolving mediator biosynthesis
    Liu, Tianye
    Xiang, Alec
    Peng, Travis
    Doran, Amanda C.
    Tracey, Kevin J.
    Barnes, Betsy J.
    Tabas, Ira
    Son, Myoungsun
    Diamond, Betty
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 116 (46) : 23254 - 23263
  • [39] A Phosphatidic Acid Binding/Nuclear Localization Motif Determines Lipin1 Function in Lipid Metabolism and Adipogenesis
    Ren, Hongmei
    Federico, Lorenzo
    Huang, Huiyan
    Sunkara, Manjula
    Drennan, Tracy
    Frohman, Michael A.
    Smyth, Susan S.
    Morris, Andrew J.
    MOLECULAR BIOLOGY OF THE CELL, 2010, 21 (18) : 3171 - 3181
  • [40] -5 Fatty Acid Desaturase FADS1 Impacts Metabolic Disease by Balancing Proinflammatory and Proresolving Lipid Mediators
    Gromovsky, Anthony D.
    Schugar, Rebecca C.
    Brown, Amanda L.
    Helsley, Robert N.
    Burrows, Amy C.
    Ferguson, Daniel
    Zhang, Renliang
    Sansbury, Brian E.
    Lee, Richard G.
    Morton, Richard E.
    Allende, Daniela S.
    Parks, John S.
    Spite, Matthew
    Brown, J. Mark
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2018, 38 (01) : 218 - 231