Regulating innate immunity with dopamine and electroacupuncture

被引：42

作者：

Chavan, Sangeeta S. ^{[1
]}

Tracey, Kevin J. ^{[1
]}

机构：

[1] Feinstein Inst Med Res, Lab Biomed Sci, Manhasset, NY USA

来源：

NATURE MEDICINE | 2014年 / 20卷 / 03期

关键词：

T-CELLS; NERVE;

D O I：

10.1038/nm.3501

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Neural circuits are able to modulate immune responses by detecting inflammatory mediators and relaying signals back to the immune system. Here, in a mouse model of sepsis, the authors show that the immune responses can be modulated by electroacupuncture, which stimulates a neural circuit that results in the release of dopamine. The mechanism, like the inflammatory reflex, is neither sympathetic nor parasympathetic. Their results show a potential way forward in developing therapies for sepsis in dopamine agonists (pages 291-295).

引用

页码：239 / 241

页数：3

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