Medication nonadherence and psychiatry

被引:93
作者
Chapman, Sarah C. E. [1 ]
Horne, Rob [1 ]
机构
[1] UCL Sch Pharm, Ctr Behav Med, London WC1H 9JP, England
基金
美国国家卫生研究院;
关键词
bipolar disorder; intervention; medication adherence; psychiatry; schizophrenia; CUSTOMIZED ADHERENCE ENHANCEMENT; BIPOLAR DISORDER; ANTIPSYCHOTIC MEDICATION; DOSING FREQUENCY; HEALTH-CARE; SCHIZOPHRENIA; PSYCHOSIS; ALLIANCE; OUTCOMES; THERAPY;
D O I
10.1097/YCO.0b013e3283642da4
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Purpose of reviewNonadherence to appropriately prescribed medication for psychiatric disorders prevents patients from realizing the full benefits of their treatment and negatively impacts on individuals, their families and the healthcare system. Understanding and reducing nonadherence is therefore a key challenge to quality care for patients with psychiatric disorders. This review highlights findings regarding the prevalence and consequence of nonadherence, barriers to adherence and new intervention methods from 2012 onwards.Recent findingsRecent research has highlighted that nonadherence is a global challenge for psychiatry and has linked nonadherence to poorer outcomes, including hospital admissions, suicide and mortality. Optimizing medication regimens can reduce nonadherence; however, often a complex interplay of factors affects individuals' motivation and ability to follow their prescription. Psychiatrists can enable patients to develop an accurate model of their illness and treatment and facilitate adherence. However, nonadherence is often a hidden issue within consultations. Novel interventions using new technologies and tailoring techniques may have the potential to reduce nonadherence.SummaryNonadherence remains a significant challenge for patients with psychiatric disorders, physicians and healthcare systems. New developments demonstrate the importance of developing tailored interventions to enable patients to overcome perceptual and practical barriers to adherence.
引用
收藏
页码:446 / 452
页数:7
相关论文
共 63 条
  • [1] Prevalence of Concomitant Oral Antipsychotic Drug Use Among Patients Treated With Long-Acting, Intramuscular, Antipsychotic Medications
    Aggarwal, Neil Krishan
    Sernyak, Michael J.
    Rosenheck, Robert A.
    [J]. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 2012, 32 (03) : 323 - 328
  • [2] Alene Menna, 2012, BMC Clin Pharmacol, V12, P10, DOI 10.1186/1472-6904-12-10
  • [3] [Anonymous], 2009, MED ADH INV PAT DEC
  • [4] [Anonymous], ANN BEHAV MED
  • [5] [Anonymous], 2013, Adherence to Long-Term Therapies: Evidence for Action, DOI DOI 10.4028/WWW.SCIENTIFIC.NET/AMM.321-324.1779
  • [6] [Anonymous], ADHERENCE ADVICE TRE
  • [7] Medication adherence and utilization in patients with schizophrenia or bipolar disorder receiving aripiprazole, quetiapine, or ziprasidone at hospital discharge: A retrospective cohort study
    Berger, Ariel
    Edelsberg, John
    Sanders, Kafi N.
    Alvir, Jose Ma J.
    Mychaskiw, Marko A.
    Oster, Gerry
    [J]. BMC PSYCHIATRY, 2012, 12
  • [8] Patients' perceptions of information received about medication prescribed for bipolar disorder: Implications for informed choice
    Bowskill, Richard
    Clatworthy, Jane
    Parham, Rhian
    Rank, Tim
    Horne, Rob
    [J]. JOURNAL OF AFFECTIVE DISORDERS, 2007, 100 (1-3) : 253 - 257
  • [9] Non-adherence with psychotropic medications in the general population
    Bulloch, Andrew G. M.
    Patten, Scott B.
    [J]. SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY, 2010, 45 (01) : 47 - 56
  • [10] Adherence Patterns With First- Versus Second-Generation Antipsychotics for Newly Diagnosed Schizophrenia in Taiwan
    Chang, Chia-Ming
    Wu, Kuan-Yi
    Liang, Hsin-Yi
    Wu, Erin Chia-Hsuan
    Chen, Chuan-Yu
    Wu, Chi-Shin
    Chen, Shaw-Ji
    Chang, Tsung-Kai
    Tsai, Hui-Ju
    [J]. PSYCHIATRIC SERVICES, 2012, 63 (05) : 504 - 507