Drying of Phytochemical Preparations in a Spouted Bed: Perspectives and Challenges

被引:14
作者
Souza, Claudia R. F. [1 ]
Oliveira, Wanderley P. [1 ]
机构
[1] Univ Sao Paulo, Fac Pharmaceut Sci Ribeirao Preto, LAPROFAR, Lab R&D Pharmaceut Proc, BR-14040903 Ribeirao Preto, SP, Brazil
基金
巴西圣保罗研究基金会;
关键词
Active phytopharmaceutical ingredient; Drying; Herbal extracts; Spouted bed; GLASS-TRANSITION; PHYSICOCHEMICAL PROPERTIES; DRIED EXTRACTS; SPRAY; STABILITY; POWDERS; DRYER; STATE; CRYSTALLIZATION; NUTRACEUTICALS;
D O I
10.1080/07373937.2012.692746
中图分类号
TQ [化学工业];
学科分类号
0817 ;
摘要
This article presents an overview of relevant issues to be considered in the development of standardized phytochemical preparations, focusing on the use of the spouted bed as a drying method. Aspects related to the effects of feed composition properties and processing parameters on system performance and product quality are addressed. From the information presented, it can be concluded that the spouted bed technology can be successfully applied for production of high-quality phytochemical preparations suitable for food and pharmaceutical purposes, considering the requirements for product safety, quality, and efficacy. Nevertheless, it should be emphasized that, at this time, the proposed technology is appropriate for small-scale production, mainly due to difficulties concerning scale-up, modeling, and the simulation of spouted bed systems, and also for predicting product properties and system behavior during operation.
引用
收藏
页码:1209 / 1226
页数:18
相关论文
共 96 条
[1]  
[Anonymous], 2006, USP 29 NF 24 US PHAR, P2603
[2]  
[Anonymous], 2006, USP 29 NF 28 US PHAR, P3017
[3]  
Barret N., 1989, DRYING 89, P415
[4]  
Bauer R, 1998, DRUG INF J, V32, P101, DOI 10.1177/009286159803200114
[5]  
BENALI M, 2002, DEV CHEM ENG MINERAL, V10, P1
[6]   Relating the stickiness property of foods undergoing drying and dried products to their surface energetics [J].
Bhandari, B ;
Howes, T .
DRYING TECHNOLOGY, 2005, 23 (04) :781-797
[7]  
Bhandari B.R., 2002, INT C INN FOOD PROC
[8]   Problems associated with spray drying of sugar-rich foods [J].
Bhandari, BR ;
Datta, N ;
Howes, T .
DRYING TECHNOLOGY, 1997, 15 (02) :671-684
[9]   Implication of glass transition for the drying and stability of dried foods [J].
Bhandari, BR ;
Howes, T .
JOURNAL OF FOOD ENGINEERING, 1999, 40 (1-2) :71-79
[10]   SPRAY-DRYING OF CONCENTRATED FRUIT JUICES [J].
BHANDARI, BR ;
SENOUSSI, A ;
DUMOULIN, ED ;
LEBERT, A .
DRYING TECHNOLOGY, 1993, 11 (05) :1081-1092