Compartmental human respiratory tract modeling of airborne dust exposure from feeding in swine buildings

被引:8
作者
Chen, JW [1 ]
Liao, CM [1 ]
Chen, SC [1 ]
机构
[1] Natl Taiwan Univ, Dept Bioenvironm Syst Engn, Taipei 10617, Taiwan
关键词
D O I
10.1080/10473289.2004.10470907
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
A simple size-dependent compartmental model was developed to describe airborne dust exposure dynamics for the human respiratory tract (HRT) in mechanically ventilated swine buildings. Transport mechanisms of airborne dust for HRT include respiration, gravitational settling, turbulent diffusive deposition, inertial impaction, interception deposition loss, and dust clearance. The dominant deposition mechanism in the lung regions was found to be the inertial impaction rate, in which the order of magnitude ranged from 10(-3) to 10(-1) sec(-1). Results demonstrate that the extrathoracic region has a higher airborne dust mass lung/indoor ratios (0.71-0.87) than do the bronchial regions (0.41-0.74), the bronchiolar region (0.12-0.61), and the alveolar-interstitial region (0.01-0.49). The predictions from the HRT model agreed favorably with the experimental deposition profiles in the nasal passage, pharynx, bronchial, bronchiolar, and alveolar-interstitial regions, whereas the rms errors of the total deposition fraction between predicted values and ICRP66 and Non-ICRP66 were 0.15 and 0.07, respectively. Simulation results show that breathing via the nose has both a higher deposition fraction and a higher exposure dose in the size ranges 0.01-10 mum than does breathing orally.
引用
收藏
页码:331 / 341
页数:11
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