Rhabdomyosarcoma Masquerading as Acute Leukemia

被引:16
作者
Shinkoda, Yuichi
Nagatoshi, Yoshihisa [1 ]
Fukano, Reiji
Nishiyama, Kenichi [2 ]
Okamura, Jun [3 ]
机构
[1] Kyushu Natl Canc Ctr, Sect Pediat, Minami Ku, Fukuoka 8111395, Japan
[2] Kyushu Natl Canc Ctr, Dept Pathol, Fukuoka 8111395, Japan
[3] Kyushu Natl Canc Ctr, Inst Clin Res, Fukuoka 8111395, Japan
关键词
bone marrow involvement; immunohistochemistry; rhabdomyosarcoma; FUSION; GENE;
D O I
10.1002/pbc.21783
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Rhabdomyosarcoma (RMS) masquerading as acute leukemia (AL) is very rare. We describe three cases with RMS without any symptoms of solid tumors. Bone marrow (BM) showed approximately 95% of blast-like abnormal cells, lacking almost all of the Surface antigens of myeloid- and lymphoid-lineage. The immunohistochemistry revealed positive of the cells for actin, desmin and myoglobin. it is important to examine BM samples by immunohistochemistry, when a flow cytometric analysis reveals an Unusual presentation. Pediatr Blood Cancer 2009;52:286-287. (C) 2008 Wiley-Liss, Inc.
引用
收藏
页码:286 / 287
页数:2
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