Facile Synthesis of Superparamagnetic Fe3O4@polyphosphazene@Au Shells for Magnetic Resonance Imaging and Photothermal Therapy

被引:113
作者
Hu, Ying [1 ]
Meng, Lingjie [1 ,3 ]
Niu, Lvye [1 ]
Lu, Qinghua [1 ,2 ]
机构
[1] Shanghai Jiao Tong Univ, Sch Chem & Chem Technol, Shanghai 200240, Peoples R China
[2] Shanghai Jiao Tong Univ, State Key Lab Met Matrix Composites, Shanghai 200240, Peoples R China
[3] Xi An Jiao Tong Univ, Sch Sci, Xian 710049, Peoples R China
基金
美国国家科学基金会;
关键词
superparamagnetic; Fe3O4; nanoparticles; polyphosphazene; Au nanoshells; GOLD NANOCAGES; NANOPARTICLES; DRUG; NANOSHELLS; PARTICLES;
D O I
10.1021/am400843d
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Multifunctional nanoparticles were prepared by directly welding superparamagnetic Fe3O4 nanoparticles and Au shells together with highly cross-linked polyphosphazene as "glue" in a facile but effective way. The as-prepared particles can simultaneously take advantages of both magnetization of Fe3O4 core for magnetic resonance imaging diagnosis and strong near-infrared absorption of Au nanoshell for photothermal therapy.
引用
收藏
页码:4586 / 4591
页数:6
相关论文
共 25 条
[1]   Nanomaterials for cancer therapy and imaging [J].
Bae, Ki Hyun ;
Chung, Hyun Jung ;
Park, Tae Gwan .
MOLECULES AND CELLS, 2011, 31 (04) :295-302
[2]   Nanomaterials: Applications in Cancer Imaging and Therapy [J].
Barreto, Jose A. ;
O'Malley, William ;
Kubeil, Manja ;
Graham, Bim ;
Stephan, Holger ;
Spiccia, Leone .
ADVANCED MATERIALS, 2011, 23 (12) :H18-H40
[3]   Photothermal imaging of nanometer-sized metal particles among scatterers [J].
Boyer, D ;
Tamarat, P ;
Maali, A ;
Lounis, B ;
Orrit, M .
SCIENCE, 2002, 297 (5584) :1160-1163
[4]   Multifunctional Fe3O4@C@Ag hybrid nanoparticles as dual modal imaging probes and near-infrared light-responsive drug delivery platform [J].
Chen, Jian ;
Guo, Zhen ;
Wang, Hai-Bao ;
Gong, Ming ;
Kong, Xiang-Kai ;
Xia, Peng ;
Chen, Qian-Wang .
BIOMATERIALS, 2013, 34 (02) :571-581
[5]   Immuno gold nanocages with tailored optical properties for targeted photothermal destruction of cancer cells [J].
Chen, Jingyi ;
Wang, Danling ;
Xi, Jiefeng ;
Au, Leslie ;
Siekkinen, Andy ;
Warsen, Addie ;
Li, Zhi-Yuan ;
Zhang, Hui ;
Xia, Younan ;
Li, Xingde .
NANO LETTERS, 2007, 7 (05) :1318-1322
[6]   Gold Nanocages as Photothermal Transducers for Cancer Treatment [J].
Chen, Jingyi ;
Glaus, Charles ;
Laforest, Richard ;
Zhang, Qiang ;
Yang, Miaoxian ;
Gidding, Michael ;
Welch, Michael J. ;
Xia, Younan .
SMALL, 2010, 6 (07) :811-817
[7]   Tumor Regression In Vivo by Photothermal Therapy Based on Gold-Nanorod-Loaded, Functional Nanocarriers [J].
Choi, Won Il ;
Kim, Ja-Young ;
Kang, Chul ;
Byeon, Clare C. ;
Kim, Young Ha ;
Tee, Giyoong .
ACS NANO, 2011, 5 (03) :1995-2003
[8]   Nanoshell-mediated photothermal therapy improves survival in a murine glioma model [J].
Day, Emily S. ;
Thompson, Patrick A. ;
Zhang, Linna ;
Lewinski, Nastassja A. ;
Ahmed, Nabil ;
Drezek, Rebekah A. ;
Blaney, Susan M. ;
West, Jennifer L. .
JOURNAL OF NEURO-ONCOLOGY, 2011, 104 (01) :55-63
[9]   Gold nanorod assisted near-infrared plasmonic photothermal therapy (PPTT) of squamous cell carcinoma in mice [J].
Dickerson, Erin B. ;
Dreaden, Erik C. ;
Huang, Xiaohua ;
El-Sayed, Ivan H. ;
Chu, Hunghao ;
Pushpanketh, Sujatha ;
McDonald, John F. ;
El-Sayed, Mostafa A. .
CANCER LETTERS, 2008, 269 (01) :57-66
[10]   Facile Synthesis of Monodisperse Superparamagnetic Fe3O4 Core@hybrid@Au Shell Nanocomposite for Bimodal Imaging and Photothermal Therapy [J].
Dong, Wenjie ;
Li, Yongsheng ;
Niu, Dechao ;
Ma, Zhi ;
Gu, Jinlou ;
Chen, Yi ;
Zhao, Wenru ;
Liu, Xiaohang ;
Liu, Changsheng ;
Shi, Jianlin .
ADVANCED MATERIALS, 2011, 23 (45) :5392-5397