A simple base-mediated amidation of aldehydes with azides

被引：31

作者：

Kulkarni, Sameer S. ^{[1
]}

Hu, Xiangdong ^{[1
]}

Manetsch, Roman ^{[1
]}

机构：

[1] Univ S Florida, Dept Chem, Tampa, FL 33620 USA

来源：

CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 12期

关键词：

PALLADIUM-CATALYZED AMINOCARBONYLATION; INTRAMOLECULAR SCHMIDT REACTIONS; AMIDE SYNTHESIS; OXIDATIVE AMIDATION; STAUDINGER LIGATION; ALKYL AZIDES; RING-EXPANSION; ARYL HALIDES; ALCOHOLS; AMINES;

D O I：

10.1039/c2cc37289d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A practical and efficient amidation reaction involving aromatic aldehydes and various azides under mild conditions is described. A broad spectrum of functional groups was tolerated, and the amides were synthesized in moderate to excellent yields, presenting an attractive alternative to the currently available synthetic methods.

引用

收藏

页码：1193 / 1195

页数：3

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