The Effect of Long COVID-19 Infection and Vaccination on Male Fertility; A Narrative Review

被引：13

作者：

Pourmasumi, Soheila ^{[1
,2
]}

Nazari, Alireza ^{[1
,3
]}

Ahmadi, Zahra ^{[4
]}

Kouni, Sophia N.

de Gregorio, Cesare ^{[5
]}

Koniari, Ioanna ^{[6
]}

Dousdampanis, Periklis ^{[7
]}

Mplani, Virginia ^{[8
]}

Plotas, Panagiotis ^{[9
]}

Assimakopoulos, Stelios ^{[10
]}

Gogos, Christos ^{[11
]}

Aidonisdis, Georgios ^{[12
]}

Roditis, Pavlos ^{[13
]}

Matsas, Nikos

Velissaris, Dimitrios ^{[14
]}

Calogiuri, Gianfranco ^{[15
,16
]}

Hung, Ming-Yow ^{[17
,18
,19
]}

Altay, Servet ^{[20
]}

Kounis, Nicholas G. ^{[21
]}

机构：

[1] Rafsanjan Univ Med Sci, Social Determinants Hlth Res Ctr, Rafsanjan 7717933777, Iran

[2] Rafsanjan Univ Med Sci, Ali Ibn Abi Talib Hosp, Clin Res Dev Unit, Rafsanjan 7717933777, Iran

[3] Rafsanjan Univ Med Sci, Sch Med, Dept Surg, Rafsanjan 7717933777, Iran

[4] Rafsanjan Univ Med Sci, Pistachio Safety Res Ctr, Rafsanjan 7717933777, Iran

[5] Univ Messina, Med Sch, Dept Clin & Expt Med, I-98122 Messina, Italy

[6] Univ Hosp South Manchester NHS Fdn Trust, Div Cardiol, Dept Internal Med, Manchester M23 9LT, England

[7] St Andrews State Gen Hosp, Dept Nephrol, Patras 26221, Greece

[8] Patras Univ Hosp, Intens Care Unit, Patras 26500, Greece

[9] Univ Patras, Dept Speech Therapy, Patras 26500, Greece

[10] Univ Patras, Div Infect Dis, Med Sch, Dept Internal Med, Patras 26500, Greece

[11] Papageorgiou Gen Hosp, COVID Unit 19, Thessaloniki 56403, Greece

[12] Interbalkan Med Ctr, Thessaloniki 57001, Greece

[13] Mamatsio Kozanis Gen Hosp, Dept Cardiol, Kozani 50100, Greece

[14] Univ Patras, Dept Internal Med, Patras 26500, Greece

[15] Civil Hosp Ninetto Melli, Pneumonol Dept, I-72027 Brindisi, Italy

[16] Univ Bari, Sect Allergol & Clin Immunol, Dept Internal Med Immunol & Infect Dis, Med Sch, I-70121 Bari, Italy

[17] Taipei Med Univ, Shuang Ho Hosp, Dept Internal Med, Div Cardiol, New Taipei City 23561, Taiwan

[18] Taipei Med Univ, Div Cardiol, Dept Internal Med, Sch Med,Coll Med, Taipei 110, Taiwan

[19] Taipei Med Univ, Taipei Heart Inst, Taipei 110, Taiwan

[20] Trakya Univ, Fac Med, Dept Cardiol, TR-22030 Edirne, Turkey

[21] Univ Patras, Div Cardiol, Med Sch, Dept Internal Med, Patras 26500, Greece

来源：

VACCINES | 2022年 / 10卷 / 12期

关键词：

infertility; COVID-19; sperm; SARS; vaccine; SARS-COV-2; INFECTION; SEMEN QUALITY; DNA-DAMAGE; CORONAVIRUS; INFERTILITY; CARE; RNA; REPRODUCTION; EXPRESSION; ORCHITIS;

D O I：

10.3390/vaccines10121982

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Earlier research has suggested that the male reproductive system could be particularly vulnerable to SARS-CoV-2 (COVID-19) infection, and infections involving this novel disease not only pose serious health threats but could also cause male infertility. Data from multi-organ research during the recent outbreak indicate that male infertility might not be diagnosed as a possible consequence of COVID-19 infection. Several review papers have summarized the etiology factors on male fertility, but to date no review paper has been published defining the effect of COVID-19 infection on male fertility. Therefore, the aim of this study is to review the published scientific evidence regarding male fertility potential, the risk of infertility during the COVID-19 pandemic, and the impact of COVID-19 vaccination on the male reproductive system. The effects of COVID-19 infection and the subsequent vaccination on seminal fluid, sperm count, sperm motility, sperm morphology, sperm viability, testes and sex hormones are particularly reviewed.

引用

页数：16

共 106 条

[1] A Review of Recent Studies on the Effects of SARS-CoV-2 Infection and SARS-CoV-2 Vaccines on Male Reproductive Health [J].

Adamyan, Leila ;

Elagin, Vladimir ;

Vechorko, Valeriy ;

Stepanian, Assia ;

Dashko, Anton ;

Doroshenko, Dmitriy ;

Aznaurova, Yana ;

Sorokin, Maxim ;

Garazha, Andrew ;

Buzdin, Anton .

MEDICAL SCIENCE MONITOR, 2022, 28

[2]

Amiri Iraj, 2007, Iran Biomed J, V11, P259

[3]

Andrade-Rocha FT, 2013, ANN CLIN LAB SCI, V43, P94

[4] COVID-19 and fertility: a virtual reality [J].

Anifandis, George ;

Messini, Christina I. ;

Daponte, Alexandros ;

Messinis, Ioannis E. .

REPRODUCTIVE BIOMEDICINE ONLINE, 2020, 41 (02) :157-159

[5] Novel associations between specific sperm morphological defects leukocytospermia [J].

Aziz, N ;

Agarwal, A ;

Lewis-Jones, I ;

Sharma, RK ;

Thomas, AJ .

FERTILITY AND STERILITY, 2004, 82 (03) :621-627

[6] Hormonal Imbalances and Psychological Scars Left Behind in Infertile Men [J].

Bak, Chong Won ;

Seok, Hyun Ha ;

Song, Seung-Hun ;

Kim, Eun Sun ;

Her, Young Sun ;

Yoon, Tae Ki .

JOURNAL OF ANDROLOGY, 2012, 33 (02) :181-189

[7]

Barda S, 2022, INT J GYNECOL OBSTET, V158, P116, DOI 10.1002/ijgo.14135

[8] Autopsy of COVID-19 patients in China [J].

Bian, Xiu-Wu .

NATIONAL SCIENCE REVIEW, 2020, 7 (09) :1414-1418

[9] Side effects among healthcare workers from a large Milan universityhospital after second dose ofBNT162b2 mRNA COVID-19 vaccine [J].

Borroni, Elisa ;

Consonni, Dario ;

Cugno, Massimo ;

Lombardi, Andrea ;

Mangioni, Davide ;

Bono, Patrizia ;

Oggioni, Massimo ;

Renteria, Sara Uceda ;

Bordini, Lorenzo ;

Nava, Carlo Domenico ;

Letzgus, Matteo ;

Silverj, Flaminia Gentiloni ;

Castaldi, Silvana ;

Rognoni, Magda ;

D'Oro, Luca Cavallieri ;

Carugno, Michele ;

Riboldi, Luciano ;

Ceriotti, Ferruccio ;

Bandera, Alessandra ;

Gori, Andrea ;

Pesatori, Angela Cecilia .

MEDICINA DEL LAVORO, 2021, 112 (06) :477-485

[10] SARS-CoV-2 and the testis: similarity with other viruses and routes of infection [J].

Cardona Maya, Walter D. ;

Du Plessis, Stefan S. ;

Velilla, Paula A. .

REPRODUCTIVE BIOMEDICINE ONLINE, 2020, 40 (06) :763-764

← 1 2 3 4 5 6 7 8 9 10 →