Methylglyoxal comes of AGE

被引：146
|
作者：
Ramasamy, R [1 ]
Yan, SF [1 ]
Schmidt, AM [1 ]
机构：
[1] Columbia Univ, Med Ctr, Dept Surg, New York, NY 10032 USA
来源：
CELL | 2006年 / 124卷 / 02期
关键词：
D O I：
10.1016/j.cell.2006.01.002
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The posttranslational modification of proteins by methylglyoxal, a highly reactive compound derived from glycolysis, may contribute to aging, diabetes, and other disorders. In this issue of Cell, Brownlee and colleagues (Yao et al., 2006) demonstrate a specific mechanism by which methylglyoxal modifies a transcriptional corepressor to enhance gene expression.
引用
收藏
页码：258 / 260
页数：3
相关论文
共 50 条
  • [31] Ageism Comes of Age
    Palmore, Erdman
    JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES, 2015, 70 (06): : 873 - 875
  • [32] With age comes resilience
    Wilson, David B.
    Fields, Melanie E.
    BLOOD, 2022, 139 (15) : 2266 - 2268
  • [33] Video comes of age
    Anderbeg, K
    COMMUNICATIONS NEWS, 2000, 37 (07): : 6 - 6
  • [34] The WFN comes of age
    Walton, John
    JOURNAL OF THE NEUROLOGICAL SCIENCES, 2008, 268 (1-2) : 1 - 5
  • [35] INFECTOLOGY COMES OF AGE
    DUNEA, G
    JOURNAL OF THE AMERICAN DENTAL ASSOCIATION, 1982, 105 (02): : 410 - 412
  • [36] Antisense comes of age
    Flanagan, WM
    CANCER AND METASTASIS REVIEWS, 1998, 17 (02) : 169 - 176
  • [37] BIOFEEDBACK COMES OF AGE
    BASMAJIAN, JV
    QUEENS QUARTERLY, 1979, 86 (01) : 30 - 38
  • [38] MEASUREMENT COMES OF AGE
    SANDBURG, D
    OFFICE ADMINISTRATION AND AUTOMATION, 1985, 46 (08): : 73 - 73
  • [39] COMSAT COMES OF AGE
    不详
    ECONOMIST, 1964, 212 (13): : 1243 - 1243
  • [40] 'AS LITERATURE COMES OF AGE'
    BUSCH, T
    POETRY, 1985, 146 (05) : 271 - 272
12345