Caesalpinia ferrea C. Mart.(Fabaceae) Phytochemistry, Ethnobotany, and Bioactivities: A Review

被引：25

作者：

Macedo, Nair Silva ^{[1
,2
,3
]}

Silveira, Zildene de Sousa ^{[1
,2
,3
]}

Bezerra, Antonio Henrique ^{[1
]}

Martins da Costa, Jose Galberto ^{[4
]}

Melo Coutinho, Henrique Douglas ^{[5
]}

Romano, Barbara ^{[6
]}

Capasso, Raffaele ^{[7
]}

Bezerra da Cunha, Francisco Assis ^{[1
]}

da Silva, Marcia Vanusa ^{[2
,3
]}

机构：

[1] Reg Univ Cariri URCA, Lab Semiarid Bioprospecting LABSEMA, BR-63105000 Crato, CE, Brazil

[2] Grad Program Biol Sci PPGCB, BR-50670901 Recife, PE, Brazil

[3] Fed Univ Pernambuco UFPE, BR-50670901 Recife, PE, Brazil

[4] Reg Univ Cariri URCA, Nat Prod Res Lab, BR-63105000 Crato, CE, Brazil

[5] Reg Univ Cariri URCA, Lab Microbiol & Mol Biol LMBM, BR-63105000 Crato, CE, Brazil

[6] Univ Naples Federico II, Dept Pharm, I-80100 Naples, Italy

[7] Univ Naples Federico II, Dept Agr Sci, I-80055 Portici, Italy

来源：

MOLECULES | 2020年 / 25卷 / 17期

关键词：

Caesalpinia ferrea; ethnoknowledge; bioactivities; phytochemicals; HPLC; TUL. LP QUEIROZ; CAESALPINIA-FERREA; MEDICINAL-PLANTS; HEALING ACTIVITY; CAATINGA; EXTRACTS; SEEDS; POLYSACCHARIDES; ANTIOXIDANT; GROWTH;

D O I：

10.3390/molecules25173831

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Caesalpinia ferrea C. Mart., popularly known as "Juca" or "Pau-ferro", belongs to the Fabaceae family, and is classified as a native and endemic species in Brazil. Numerous studies that portray its ethnobotany, chemical composition, and biological activities exist in the literature. The present study aimed to systematically review publications addressing the botanical aspects, uses in popular medicine, phytochemical composition, and bioactivities ofC. ferrea. The searches focused on publications from 2015 to March 2020 using the Scopus, Periodicos Capes, PubMed, Google Scholar, and ScienceDirect databases. The leaves, fruits, seeds, and bark fromC. ferreaare used in popular medicine to treat disorders affecting several systems, including the circulatory, immune, cardiovascular, digestive, respiratory, genitourinary, musculoskeletal, and conjunctive systems. The most commonly found chemical classes in phytochemical studies are flavonoids, polyphenols, terpenoids, tannins, saponins, steroids, and other phenolic compounds. The biological properties of the extracts and isolated compounds ofC. ferreamost cited in the literature were antibacterial, antifungal, antioxidant, antiproliferative, anti-inflammatory, and healing potential. However, further studies are still needed to clarify a link between its traditional uses, the active compounds, and the reported pharmacological activities, as well as detailed research to determine the toxicological profile ofC. ferrea.

引用

页数：33

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