Nanosphere molecularly imprinted polymers doped with gold nanoparticles for high selectivity molecular sensors

被引：40
作者：
Shahar, Tehila [1 ]
Sicron, Tama [1 ]
Mandler, Daniel [1 ]
机构：
[1] Hebrew Univ Jerusalem, Inst Chem, IL-9190401 Jerusalem, Israel
来源：
NANO RESEARCH | 2017年 / 10卷 / 03期
关键词：
molecularly imprinted polymers; surface enhanced Raman scattering (SERS); gold nanoparticles; Sudan TV; doping; ENHANCED RAMAN-SCATTERING; PRECIPITATION POLYMERIZATION; AU NANOPARTICLES; ACID; FABRICATION; PARTICLES; CORE; MICROSPHERES; RECOGNITION; NANOSENSORS;
D O I：
10.1007/s12274-016-1366-5
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
We report the first attempt of using molecularly imprinted polymers (MIPs) in the shape of nanoparticles that were doped with gold nanoparticles (AuNPs) for surface enhanced Raman scattering (SERS)-based sensing of molecular species. Specifically, AuNPs doped molecularly imprinted nano-spheres (AuNPs@nanoMIPs) were synthesized by one-pot precipitation polymerization using Sudan IV as the template for the SERS sensing. The AuNPs@nanoMIPs were characterized by various modes of scanning transmission electron microscopy (STEM) that showed the exact location of the AuNPs inside the MIP particles. The effects of Au concentration and solution stirring on the shape and the polydispersity of the particles were studied. Significant enhancement of the Raman signals was observed only when the MIP particles were doped with the AuNPs. The SERS signal improved significantly with increase in the Au concentration inside the AuNPs@nanoMIPs. Selectivity measurements of the Sudan IV imprinted AuNPs@nanoMIPs carried out with different Sudan derivatives showed high selectivity of the AuNPs-doped MIP particles.
引用
收藏
页码：1056 / 1063
页数：8
相关论文
共 33 条
[1]   Fabrication of a new electrochemical sensor based on a new nano-molecularly imprinted polymer for highly selective and sensitive determination of tramadol in human urine samples [J].
Afkhami, Abbas ;
Ghaedi, Hamed ;
Madrakian, Tayyebeh ;
Ahmadi, Mazaher ;
Mahmood-Kashani, Hedye .
BIOSENSORS & BIOELECTRONICS, 2013, 44 :34-40
[2]   Nanocomposites of Gold Nanoparticles@Molecularly Imprinted Polymers: Chemistry, Processing, and Applications in Sensors [J].
Ahmad, Randa ;
Griffete, Nebewia ;
Lamouri, Aazdine ;
Felidj, Nordin ;
Chehimi, Mohamed M. ;
Mangeney, Claire .
CHEMISTRY OF MATERIALS, 2015, 27 (16) :5464-5478
[3]   Water-soluble plasmonic nanosensors with synthetic receptors for label-free detection of folic acid [J].
Ahmad, Randa ;
Felidj, Nordin ;
Boubekeur-Lecaque, Leila ;
Lau-Truong, Stephanie ;
Gam-Derouich, Sarra ;
Decorse, Philippe ;
Lamouri, Aazdine ;
Mangeney, Claire .
CHEMICAL COMMUNICATIONS, 2015, 51 (47) :9678-9681
[4]   Direct potentiometric quantification of histamine using solid-phase imprinted nanoparticles as recognition elements [J].
Basozabal, Itsaso ;
Guerreiro, Antonio ;
Gomez-Caballero, Alberto ;
Aranzazu Goicolea, M. ;
Barrio, Ramon J. .
BIOSENSORS & BIOELECTRONICS, 2014, 58 :138-144
[5]   Chemical Nanosensors Based on Composite Molecularly Imprinted Polymer Particles and Surface-Enhanced Raman Scattering [J].
Bompart, Marc ;
De Wilde, Yannick ;
Haupt, Karsten .
ADVANCED MATERIALS, 2010, 22 (21) :2343-2348
[6]   Sensitive detection of 2,4,6-trinitrotoluene by tridimensional monitoring of molecularly imprinted polymer with optical fiber and five-branched gold nanostars [J].
Cennamo, N. ;
Dona, A. ;
Pallavicini, P. ;
D'Agostino, G. ;
Dacarro, G. ;
Zeni, L. ;
Pesavento, M. .
SENSORS AND ACTUATORS B-CHEMICAL, 2015, 208 :291-298
[7]   Surface molecular imprinting onto silver microspheres for surface enhanced Raman scattering applications [J].
Chang, Limin ;
Ding, Yan ;
Li, Xin .
BIOSENSORS & BIOELECTRONICS, 2013, 50 :106-110
[8]   Molecular imprinted polymers for separation science: A review of reviews [J].
Cheong, Won Jo ;
Yang, Song Hee ;
Ali, Faiz .
JOURNAL OF SEPARATION SCIENCE, 2013, 36 (03) :609-628
[9]   Estrone Specific Molecularly Imprinted Polymeric Nanospheres: Synthesis, Characterization and Applications for Electrochemical Sensor Development [J].
Congur, Gulsah ;
Senay, Hilal ;
Turkcan, Ceren ;
Canavar, Ece ;
Erdem, Arzum ;
Akgol, Sinan .
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2013, 16 (07) :503-510
[10]   The fabrication of a new electrochemical sensor based on electropolymerization of nanocomposite gold nanoparticle-molecularly imprinted polymer for determination of valganciclovir [J].
Gholivand, M. B. ;
Torkashvand, M. .
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2016, 59 :594-603
1234