The saccus vasculosus of fish is a sensor of seasonal changes in day length

被引：129

作者：

Nakane, Yusuke ^{[1
]}

Ikegami, Keisuke ^{[1
]}

Iigo, Masayuki ^{[2
,3
,4
,5
]}

Ono, Hiroko ^{[1
]}

Takeda, Korenori ^{[2
,5
,6
]}

Takahashi, Daisuke ^{[2
]}

Uesaka, Maiko ^{[2
]}

Kimijima, Meita ^{[2
]}

Hashimoto, Ramu ^{[2
]}

Arai, Natsumi ^{[2
]}

Suga, Takuya ^{[2
]}

Kosuge, Katsuya ^{[2
]}

Abe, Tomotaka ^{[2
,5
]}

Maeda, Ryosuke ^{[1
]}

Senga, Takumi ^{[1
]}

Amiya, Noriko ^{[7
]}

Azuma, Teruo ^{[8
]}

Amano, Masafumi ^{[7
]}

Abe, Hideki ^{[9
]}

Yamamoto, Naoyuki ^{[9
]}

Yoshimura, Takashi ^{[1
,10
,11
,12
]}

机构：

[1] Nagoya Univ, Grad Sch Bioagr Sci, Dept Appl Mol Biosci, Physiol Anim Lab,Chikusa Ku, Nagoya, Aichi 4648601, Japan

[2] Utsunomiya Univ, Fac Agr, Dept Appl Biochem, Utsunomiya, Tochigi 3218505, Japan

[3] Utsunomiya Univ, Ctr Biosci Res & Educ C Bio, Utsunomiya, Tochigi 3218505, Japan

[4] Utsunomiya Univ, Ctr Opt Res & Educ, Utsunomiya, Tochigi 3218585, Japan

[5] Tokyo Univ Agr & Technol, United Grad Sch Agr Sci, Dept Appl Life Sci, Fuchu, Tokyo 1838509, Japan

[6] Tochigi Prefectural Fisheries Expt Stn, Ohtawara, Tochigi 3240404, Japan

[7] Kitasato Univ, Sch Marine Biosci, Lab Fish Physiol, Minami Ku, Sagamihara, Kanagawa 2520373, Japan

[8] Natl Res Inst Fisheries Sci, Freshwater Fisheries Res Dept, Nikko, Tochigi 3211661, Japan

[9] Nagoya Univ, Grad Sch Bioagr Sci, Dept Biol Mech & Funct, Lab Fish Biol,Chikusa Ku, Nagoya, Aichi 4648601, Japan

[10] Nagoya Univ, Grad Sch Bioagr Sci, Avian Biosci Res Ctr, Chikusa Ku, Nagoya, Aichi 4648601, Japan

[11] Nagoya Univ, Inst Transformat Biomol WPI ITbM, Chikusa Ku, Nagoya, Aichi 4648601, Japan

[12] Natl Inst Basic Biol, Dept Environm Biol, Okazaki, Aichi 4448585, Japan

来源：

NATURE COMMUNICATIONS | 2013年 / 4卷

关键词：

PHOTOPERIODIC SIGNAL-TRANSDUCTION; GONADOTROPIN-RELEASING-HORMONE; CELL-TYPES; SYSTEM; ONCORHYNCHUS; EVOLUTION; CLOCK; THYROTROPIN; INSIGHTS; SALMON;

D O I：

10.1038/ncomms3108

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The pars tuberalis of the pituitary gland is the regulatory hub for seasonal reproduction in birds and mammals. Although fish also exhibit robust seasonal responses, they do not possess an anatomically distinct pars tuberalis. Here we report that the saccus vasculosus of fish is a seasonal sensor. We observe expression of key genes regulating seasonal reproduction and rhodopsin family genes in the saccus vasculosus of masu salmon. Immunohistochemical studies demonstrate that all of these genes are expressed in the coronet cells of the saccus vasculosus, suggesting the existence of a photoperiodic signalling pathway from light input to neuroendocrine output. In addition, isolated saccus vasculosus has the capacity to respond to photoperiodic signals, and its removal abolishes photoperiodic response of the gonad. Although the physiological role of the saccus vasculosus has been a mystery for several centuries, our findings indicate that the saccus vasculosus acts as a sensor of seasonal changes in day length in fish.

引用

页数：7

共 39 条

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[2] SALMON GONADOTROPIN-RELEASING-HORMONE AND GONADOTROPIN ARE INVOLVED IN PRECOCIOUS MATURATION INDUCED BY PHOTOPERIOD MANIPULATION IN UNDERYEARLING MALE MASU SALMON, ONCORHYNCHUS-MASOU [J].