FDG-PET in Fever of Unknown Origin

被引：61

作者：

Kouijzer, Ilse J. E. ^{[1
]}

Bleeker-Rovers, Chantal P. ^{[1
,2
]}

Oyen, Wim J. G. ^{[2
,3
]}

机构：

[1] Radboud Univ Nijmegen, Med Ctr, Dept Internal Med, NL-6500 HB Nijmegen, Netherlands

[2] N4i, Nijmegen, Netherlands

[3] Radboud Univ Nijmegen, Med Ctr, Dept Nucl Med, NL-6500 HB Nijmegen, Netherlands

来源：

SEMINARS IN NUCLEAR MEDICINE | 2013年 / 43卷 / 05期

关键词：

POSITRON-EMISSION-TOMOGRAPHY; STRUCTURED DIAGNOSTIC PROTOCOL; F-18-FDG PET; PROSPECTIVE MULTICENTER; IN-111-GRANULOCYTE SCINTIGRAPHY; CLINICAL-VALUE; INFLAMMATION; EXPERIENCE;

D O I：

10.1053/j.semnuclmed.2013.04.005

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Fever of unknown origin (FUO) is commonly defined as fever higher than 38.3 degrees C on several occasions during at least 3 weeks with uncertain diagnosis after a number of obligatory tests. FUO remains a clinical challenge as no diagnosis is reached in up to 50% of cases. In general, infection accounts for one-fourth of cases of FUO, followed by neoplasm and noninfectious inflammatory diseases. FDG-PET is a sensitive diagnostic technique for the evaluation of FUO. Especially integrated imaging combining PET and CT facilitates anatomical localization of focally increased FDG uptake, thereby guiding further diagnostic tests to achieve a final diagnosis. FDG-PET/CT appears to be a more sensitive diagnostic tool in FUO than stand-alone FDG-PET, because of the precise anatomical localization of small lesions and better differentiation between physiological and pathologic metabolic foci. With FDG-PET/CT becoming widely available, FDG-PET/CT should be a routine procedure in the workup of FUO. (C) 2013 Elsevier Inc. All rights reserved.

引用

页码：333 / 339

页数：7