Can Stroma Reaction Predict Cancer Lethality?

被引：20

作者：

Freeman, Michael R. ^{[1
,2
,3
]}

Li, Quanlin ^{[4
]}

Chung, Leland W. K. ^{[1
,2
]}

机构：

[1] Cedars Sinai Med Ctr, Samuel Oschin Comprehens Canc Ctr, Dept Med, Los Angeles, CA 90048 USA

[2] Cedars Sinai Med Ctr, Samuel Oschin Comprehens Canc Ctr, Dept Surg, Los Angeles, CA 90048 USA

[3] Cedars Sinai Med Ctr, Samuel Oschin Comprehens Canc Ctr, Dept Biomed Sci, Los Angeles, CA 90048 USA

[4] Cedars Sinai Med Ctr, Samuel Oschin Comprehens Canc Ctr, Biostat & Bioinformat Ctr, Los Angeles, CA 90048 USA

来源：

CLINICAL CANCER RESEARCH | 2013年 / 19卷 / 18期

关键词：

BREAST-CARCINOMA; PROSTATE-CANCER; GROWTH; CELLS;

D O I：

10.1158/1078-0432.CCR-13-1694

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Stromal features in carcinomas may provide a relatively consistent means to stratify patients afflicted with solid tumors. Stroma-derived transcriptome signatures can now be used to make predictions about patient survival, suggesting the potential for their clinical application in precision medicine to predict disease progression and emergence of therapeutic resistance. (C) 2013 AACR.

引用

页码：4905 / 4907

页数：3

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