A High-Quality Biobank Supports Breast Cancer Research in Harbin, China

被引：8

作者：

Zhang, Guangwen ^{[1
]}

Xia, Bingshu ^{[2
,3
]}

Liu, Tong ^{[2
]}

Zhang, Jinfeng ^{[2
]}

Niu, Ming ^{[2
]}

Xu, Shouping ^{[2
]}

Bai, Xianan ^{[2
]}

You, Zilong ^{[2
]}

Xu, Qiuju ^{[1
]}

Zhang, Yin ^{[1
]}

Cleveland, Joseph ^{[3
,4
]}

Zhang, Dekai ^{[2
,3
]}

Pang, Da ^{[1
,2
,5
]}

机构：

[1] Harbin Med Univ, Breast Canc Biobank, Canc Hosp, Harbin, Peoples R China

[2] Harbin Med Univ, Dept Breast Surg, Affiliated Hosp 3, Harbin, Peoples R China

[3] Texas A&M Univ, Hlth Sci Ctr, Inst Biosci & Technol, Ctr Infect & Inflammatory Dis, Houston, TX USA

[4] Texas A&M Univ, Hlth Sci Ctr, Coll Med, Houston, TX USA

[5] Heilongjiang Med Sci Inst, Tumor Res Inst, Harbin, Peoples R China

来源：

BIOPRESERVATION AND BIOBANKING | 2016年 / 14卷 / 05期

关键词：

biobank; breast cancer; storage conditions; high-quality samples; RNA INTEGRITY NUMBER; TUMOR-STROMA RATIO; FROZEN TISSUE; STORAGE; QUANTIFICATION; DEGRADATION; VALIDATION; CARCINOMA; SURVIVAL; SYSTEM;

D O I：

10.1089/bio.2015.0010

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

We established a standard breast cancer biobank at Harbin Medical University Cancer Hospital (HMUCH) in 2009. More than 100,000 biospecimens, including high-quality human breast cancer samples, matched blood samples, and adjacent normal tissues, were collected from patients and healthy donors in HMUCH and were then deposited in the repository. We reported the establishment of a biobank in our hospital and its crucial role in translational medicine research. We stored, processed, and distributed qualified biological specimens in accordance with international standard operating procedures. We also summarized the utilization of this biobank and its influence on research projects over the years since its establishment. Therefore, we can verify specific biomarkers that may aid in the development of targeted breast cancer therapies by using high-quality, well-annotated tissue samples provided by the biobank.

引用

页码：375 / 382

页数：8

共 31 条

[1] [Anonymous], 2012, Biopreserv Biobank, V10, P79, DOI 10.1089/bio.2012.1022
[2] Bertucci Francois, 2008, J Biol, V7, P6, DOI 10.1186/jbiol67
[3] EFFECTS OF STORAGE-TEMPERATURE ON VIABLE BIOPROSTHETIC HEART-VALVES
BROCKBANK, KGM
CARPENTER, JF
DAWSON, PE
[J]. CRYOBIOLOGY, 1992, 29 (05) : 537 - 542
[4] Caboux EPA, 2007, 2 WHO INT AG RES CAN
[5] Validation of Vacuum-Based Refrigerated System for Biobanking Tissue Preservation: Analysis of Cellular Morphology, Protein Stability, and RNA Quality
Condelli, Valentina
Lettini, Giacomo
Patitucci, Giuseppe
D'Auria, Fiorella
D'Amico, Michele
Vita, Giulia
Musto, Pellegrino
Cuomo, Carmela
Landriscina, Matteo
[J]. BIOPRESERVATION AND BIOBANKING, 2014, 12 (01) : 35 - 45
[6] CRAWFORD D, 1984, CANCER RES, V44, P2348
[7] Tumor-stroma ratio in the primary tumor is a prognostic factor in early breast cancer patients, especially in triple-negative carcinoma patients
de Kruijf, Esther M.
van Nes, Johanna G. H.
de Velde, Cornelis J. H. van
Putter, Hein
Smit, Vincent T. H. B. M.
Liefers, Gerrit Jan
Kuppen, Peter J. K.
Tollenaar, Rob A. E. M.
Mesker, Wilma E.
[J]. BREAST CANCER RESEARCH AND TREATMENT, 2011, 125 (03) : 687 - 696
[8] Prognostic significance of the tumor-stroma ratio: validation study in node-negative premenopausal breast cancer patients from the EORTC perioperative chemotherapy (POP) trial (10854)
Dekker, T. J. A.
van de Velde, C. J. H.
van Pelt, G. W.
Kroep, J. R.
Julien, J-P.
Smit, V. T. H. B. M.
Tollenaar, R. A. E. M.
Mesker, W. E.
[J]. BREAST CANCER RESEARCH AND TREATMENT, 2013, 139 (02) : 371 - 379
[9] Breast cancer in China
Fan, Lei
Strasser-Weippl, Kathrin
Li, Jun-Jie
St Louis, Jessica
Finkelstein, Dianne M.
Yu, Ke-Da
Chen, Wan-Qing
Shao, Zhi-Ming
Goss, Paul E.
[J]. LANCET ONCOLOGY, 2014, 15 (07) : E279 - E289
[10] The Value of a Tumor Bank in the Development of Cancer Research in Brazil: 13 Years of Experience at the A C Camargo Hospital
Froes Marques Campos, Antonio Hugo Jose
Silva, Andre Abreu
De Carvalho Mota, Louise Danielle
Olivieri, Eloisa Ribeiro
Prescinoti, Vera Cristina
Patrao, Diogo
Camargo, Luiz Paulo
Brentani, Helena
Carraro, Dirce Maria
Brentani, Ricardo Renzo
Soares, Fernando Augusto
[J]. BIOPRESERVATION AND BIOBANKING, 2012, 10 (02) : 168 - 173

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