OMEGA 3 FATTY ACIDS IN PSYCHIATRY

被引:1
作者
Pavlovic, D. M. [1 ]
Pavlovic, Aleksandra M. [2 ,3 ]
Lackovic, Maja [2 ,4 ]
机构
[1] Univ Belgrade, Fac Special Educ & Rehabil, Belgrade 11000, Serbia
[2] Univ Belgrade, Fac Med, Belgrade 11000, Serbia
[3] Clin Ctr Serbia, Neurol Clin, Belgrade 11000, Serbia
[4] Clin Ctr Serbia, Psychiat Clin, Belgrade 11000, Serbia
关键词
Omega 3 fatty acids; psychiatry; depression; bipolar disorder; schizophrenia; POLYUNSATURATED FATTY-ACIDS; N-3; DHA; SUPPLEMENTATION; PREVENTION; DEPRESSION; COGNITION; HEALTH; CORTEX; EPA;
D O I
10.2298/ABS1301043P
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Omega-3 long-chain polyunsaturated fatty acids (omega-3 LC-PUFAs) are thought to be important for normal dopaminergic, glutamatergic and serotonergic neurotransmission. Depression is less prevalent in societies with high fish consumption, and depressed patients have significantly lower red blood cell omega-3 levels. Studies with omega-3 supplementation have led to controversial results. A significantly longer remission of bipolar symptomatology has been confirmed from a high-dose DHA and EPA mixture. Greater seafood consumption per capita has been connected with a lower prevalence of bipolar spectrum disorders. Reduced levels of omega-6 and omega-3 PUFAs were found in patients with schizophrenia.
引用
收藏
页码:43 / 46
页数:4
相关论文
共 31 条
  • [1] Long-Chain ω-3 Fatty Acids for Indicated Prevention of Psychotic Disorders A Randomized, Placebo-Controlled Trial
    Amminger, G. Paul
    Schafer, Miriam R.
    Papageorgiou, Konstantinos
    Klier, Claudia M.
    Cotton, Sue M.
    Harrigan, Susan M.
    Mackinnon, Andrew
    McGorry, Patrick D.
    Berger, Gregor E.
    [J]. ARCHIVES OF GENERAL PSYCHIATRY, 2010, 67 (02) : 146 - 154
  • [2] Updated systematic review and meta-analysis of the effects of n-3 long-chain polyunsaturated fatty acids on depressed mood
    Appleton, Katherine M.
    Rogers, Peter J.
    Ness, Andrew R.
    [J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 2010, 91 (03) : 757 - 770
  • [3] Distribution, interconversion, and dose response of n-3 fatty acids in humans
    Arterburn, Linda M.
    Hall, Eileen Bailey
    Oken, Harry
    [J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 2006, 83 (06) : 1467S - 1476S
  • [4] Balanzá-Martínez V, 2011, EXPERT REV NEUROTHER, V11, P1029, DOI [10.1586/ern.11.42, 10.1586/ERN.11.42]
  • [5] Role of Omega-3 Fatty Acids for Prevention or Treatment of Perinatal Depression
    Borja-Hart, Nancy L.
    Marino, Jehan
    [J]. PHARMACOTHERAPY, 2010, 30 (02): : 210 - 216
  • [6] Supplementation of a low dose of DHA or DHA plus AA does not prevent peripartum depressive symptoms in a small population based sample
    Doornbos, B.
    van Goor, S. A.
    Dijck-Brouwer, D. A. J.
    Schaafsma, A.
    Korf, J.
    Muskiet, F. A. J.
    [J]. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 2009, 33 (01) : 49 - 52
  • [7] FATTY-ACID COMPOSITION OF PLASMA-LIPIDS IN GREENLAND ESKIMOS
    DYERBERG, J
    BANG, HO
    HJORNE, N
    [J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 1975, 28 (09) : 958 - 966
  • [8] Essential fatty acids, lipid membrane abnormalities, and the diagnosis and treatment of schizophrenia
    Fenton, WS
    Hibbeln, J
    Knable, M
    [J]. BIOLOGICAL PSYCHIATRY, 2000, 47 (01) : 8 - 21
  • [9] Omega-3 fatty acids and perinatal depression: A review of the literature and recommendations for future research
    Freeman, M. P.
    [J]. PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, 2006, 75 (4-5): : 291 - 297
  • [10] Omega-3 Fatty Acids in Major Depressive Disorder
    Freeman, Marlene P.
    [J]. JOURNAL OF CLINICAL PSYCHIATRY, 2009, 70 : 7 - 11