In vivo selection of fluoroquinolone-resistant Escherichia coli isolates expressing plasmid-mediated quinolone resistance and expanded-spectrum β-lactamase

被引:74
作者
Poirel, L
Pitout, JDD
Calvo, L
Rodriguez-Martinez, JM
Church, D
Nordmann, P
机构
[1] Univ Paris 11, Fac Med Paris Sud, Hop Bicetre, Assistance Publ Hop Paris,Serv Bacteriol Virol, F-94275 Le Kremlin Bicetre, France
[2] Univ Calgary, Div Microbiol, Calgary Lab Serv, Calgary, AB, Canada
[3] Univ Calgary, Dept Pathol & Lab Med, Calgary, AB, Canada
[4] Univ Calgary, Dept Microbiol & Infect Dis, Calgary, AB, Canada
[5] Univ Calgary, Dept Med, Calgary, AB, Canada
[6] Univ Sevilla, Univ Hosp Virgen Macarena, Seville, Spain
关键词
D O I
10.1128/AAC.50.4.1525-1527.2006
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
A ciprofloxacin-resistant Escherichia coli isolate, isolate 1B, was obtained from a urinary specimen of a Canadian patient treated with norfloxacin for infection due to a ciprofloxacin-susceptible isolate, isolate 1A. Both isolates harbored a plasmid-encoded sul1-type integron with qnrA1 and bla(VEB-1) genes. Isolate 1B had amino acid substitutions in gyrase and topoisomerase.
引用
收藏
页码:1525 / 1527
页数:3
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