Microfluidic Flow Rate Detection With a Large Dynamic Range by Optical Manipulation

被引：29

作者：

Gong, Yuan ^{[1
]}

Liu, Qun-Feng ^{[2
]}

Zhang, Chen-Lin ^{[2
]}

Wu, Yu ^{[1
]}

Rao, Yun-Jiang ^{[2
]}

Peng, Gang-Ding ^{[3
]}

机构：

[1] Univ Elect Sci & Technol China, Ctr Informat BioMed, Key Lab Opt Fiber Sensing & Commun, Minist Educ China, Chengdu 611731, Peoples R China

[2] Univ Elect Sci & Technol China, Key Lab Opt Fiber Sensing & Commun, Minist Educ, Chengdu 611731, Peoples R China

[3] Univ New S Wales, Sch Elect Engn & Telecommun, Sydney, NSW 2052, Australia

来源：

IEEE PHOTONICS TECHNOLOGY LETTERS | 2015年 / 27卷 / 23期

基金：

中国国家自然科学基金;

关键词：

Optofluidics; fiber optic sensors; optical manipulation; flow rate sensor; ON-A-CHIP; WATER;

D O I：

10.1109/LPT.2015.2473836

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Sensitive flow rate detection with a large dynamic range is highly desirable for the lab-on-a-chip applications. We demonstrate an optofluidic flow rate detection method based on the optical manipulation of a single microparticle by a cleaved single-mode fiber (SMF). The microbalance between the optical force and the flow force on the single polystyrene microparticle was used as a new strategy for the detection. Due to the inverse sensitivity, the limit of detection is pushed down to 20 nL/min by detecting the manipulation length as a function of the flow rate. The measurement range of about three orders of magnitude is achieved. The experimental results indicate that the method produces a good repeatability for the flow rate measurement. The cleaved SMF for the optofluidic manipulation also enables low cost, repeatable, and mass production of the sensing device.

引用

页码：2508 / 2511

页数：4

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