Statistical inference for right-censored data with nonignorable missing censoring indicators

被引:1
作者
Sun ZhiHua [1 ]
Xie TianFa [2 ]
Liang Hua [3 ]
机构
[1] Univ Chinese Acad Sci, Sch Math Sci, Beijing 100049, Peoples R China
[2] Beijing Univ Technol, Coll Appl Sci, Beijing 100124, Peoples R China
[3] Univ Rochester, Dept Biostat & Computat Biol, Rochester, NY 14642 USA
基金
中国博士后科学基金; 美国国家科学基金会; 中国国家自然科学基金;
关键词
MAR mechanism testing; nonignorable missing censoring indicators; survival function; quasi-likelihood; PRODUCT-LIMIT ESTIMATORS; NONPARAMETRIC-ESTIMATION; REGRESSION; FAILURE; MODELS;
D O I
10.1007/s11425-012-4492-x
中图分类号
O29 [应用数学];
学科分类号
070104 ;
摘要
We consider the statistical inference for right-censored data when censoring indicators are missing but nonignorable, and propose an adjusted imputation product-limit estimator. The proposed estimator is shown to be consistent and converges to a Gaussian process. Furthermore, we develop an empirical process-based testing method to check the MAR (missing at random) mechanism, and establish asymptotic properties for the proposed test statistic. To determine the critical value of the test, a consistent model-based bootstrap method is suggested. We conduct simulation studies to evaluate the numerical performance of the proposed method and compare it with existing methods. We also analyze a real data set from a breast cancer study for an illustration.
引用
收藏
页码:1263 / 1278
页数:16
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