Rethinking Risk for Pneumococcal Disease in Adults: The Role of Risk Stacking

被引：28

作者：

Pelton, Stephen I. ^{[1
,2
,3
]}

Shea, Kimberly M. ^{[1
,2
]}

Weycker, Derek ^{[4
]}

Farkouh, Raymond A. ^{[5
]}

Strutton, David R. ^{[5
]}

Edelsberg, John ^{[4
]}

机构：

[1] Boston Univ, Sch Med, Brookline, MA USA

[2] Boston Univ, Sch Publ Hlth, Brookline, MA USA

[3] Boston Med Ctr, Brookline, MA USA

[4] Policy Anal Inc, Brookline, MA USA

[5] Pfizer Inc, Collegeville, PA USA

来源：

OPEN FORUM INFECTIOUS DISEASES | 2015年 / 2卷 / 01期

关键词：

comorbidity; pneumococcal infections; pneumonia; Streptococcus pneumonia; PNEUMONIA; INFLAMMATION; SEROTYPES; CHILDREN;

D O I：

10.1093/ofid/ofv020

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Using data from 3 private healthcare claims repositories, we evaluated the incidence of pneumococcal disease among adults with US Advisory Committee on Immunization Practices (ACIP) defined at-risk conditions or rheumatoid arthritis, lupus, Crohn's disease, and neuromuscular disorder/seizures and those with traditional high-risk conditions. We observed that adults with >= 2 concurrent comorbid conditions had pneumococcal disease incidence rates that were as high as or higher than rates observed in those with traditional high-risk conditions.

引用

页数：5

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