Three-dimensional imaging of normal skin and nonmelanoma skin cancer with cellular resolution using Gabor domain optical coherence microscopy

被引：45

作者：

Lee, Kye-Sung ^{[1
]}

Zhao, Huimin ^{[1
]}

Ibrahim, Sherrif F. ^{[2
]}

Meemon, Natthani ^{[1
]}

Khoudeir, Laura ^{[1
]}

Rolland, Jannick P. ^{[1
]}

机构：

[1] Univ Rochester, Inst Opt, Rochester, NY 14627 USA

[2] Univ Rochester, Med Ctr, Dept Dermatol, Rochester, NY 14623 USA

来源：

JOURNAL OF BIOMEDICAL OPTICS | 2012年 / 17卷 / 12期

基金：

美国国家科学基金会;

关键词：

medical imaging; imaging coherence; biomedical optics; imaging systems; VIVO HUMAN SKIN; IN-VIVO; LIQUID LENS; TOMOGRAPHY; CARCINOMA; DERMATOLOGY; THICKNESS; SPEED; HISTOLOGY; DISEASES;

D O I：

10.1117/1.JBO.17.12.126006

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We investigate morphological differences in three-dimensional (3-D) images with cellular resolution between nonmelanoma skin cancer and normal skin using Gabor domain optical coherence microscopy. As a result, we show for the first time cellular optical coherence images of 3-D features differentiating cancerous skin from normal skin. In addition, in vivo volumetric images of normal skin from different anatomic locations are shown and compared. (c) 2012 Society of Photo-Optical Instrumentation Engineers (SPIE). [DOI: 10.1117/1.JBO.17.12.126006]

引用

页数：8

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