Three-dimensional imaging of normal skin and nonmelanoma skin cancer with cellular resolution using Gabor domain optical coherence microscopy

被引：45
|
作者：
Lee, Kye-Sung [1 ]
Zhao, Huimin [1 ]
Ibrahim, Sherrif F. [2 ]
Meemon, Natthani [1 ]
Khoudeir, Laura [1 ]
Rolland, Jannick P. [1 ]
机构：
[1] Univ Rochester, Inst Opt, Rochester, NY 14627 USA
[2] Univ Rochester, Med Ctr, Dept Dermatol, Rochester, NY 14623 USA
来源：
JOURNAL OF BIOMEDICAL OPTICS | 2012年 / 17卷 / 12期
基金：
美国国家科学基金会;
关键词：
medical imaging; imaging coherence; biomedical optics; imaging systems; VIVO HUMAN SKIN; IN-VIVO; LIQUID LENS; TOMOGRAPHY; CARCINOMA; DERMATOLOGY; THICKNESS; SPEED; HISTOLOGY; DISEASES;
D O I：
10.1117/1.JBO.17.12.126006
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
We investigate morphological differences in three-dimensional (3-D) images with cellular resolution between nonmelanoma skin cancer and normal skin using Gabor domain optical coherence microscopy. As a result, we show for the first time cellular optical coherence images of 3-D features differentiating cancerous skin from normal skin. In addition, in vivo volumetric images of normal skin from different anatomic locations are shown and compared. (c) 2012 Society of Photo-Optical Instrumentation Engineers (SPIE). [DOI: 10.1117/1.JBO.17.12.126006]
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页数：8
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