Specific changes in hippocampal spatial codes predict spatial working memory performance

被引：13

作者：

Puryear, CB ^{[1
]}

King, M ^{[1
]}

Mizumori, SJY ^{[1
]}

机构：

[1] Univ Washington, Dept Psychol, Seattle, WA 98195 USA

来源：

BEHAVIOURAL BRAIN RESEARCH | 2006年 / 169卷 / 01期

关键词：

place cells; place fields; behavior; spatial learning; single units;

D O I：

10.1016/j.bbr.2005.12.007

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

This study examined the relationship between hippocampal place fields and spatial working memory. Place cells were recorded while rats solved a spatial working memory task in light and dark testing conditions. Rats made significantly more errors when tested in darkness, and although place fields changed in multiple ways in darkness, only changes in place field specificity predicted the degree of impaired spatial memory. This finding suggests that more spatially distinct place fields may contribute to hippocampal-dependent mnemonic functions. (C) 2006 Elsevier B.V. All rights reserved.

引用

页码：168 / 175

页数：8

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