Template-constrained somatostatin analogues:: A biphenyl linker induces a type-V′ turn

被引:18
作者
Cheng, RP
Suich, DJ
Cheng, H
Roder, H
DeGrado, WF
机构
[1] Fox Chase Canc Ctr, Inst Canc Res, Philadelphia, PA 19111 USA
[2] Univ Penn, Sch Med, Dept Biochem & Biophys, Johnson Res Fdn, Philadelphia, PA 19104 USA
关键词
D O I
10.1021/ja0116932
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
引用
收藏
页码:12710 / 12711
页数:2
相关论文
共 47 条
[41]   Identification of a potent heterocyclic ligand to somatostatin receptor subtype 5 by the synthesis and screening of β-turn mimetic libraries [J].
Souers, AJ ;
Virgilio, AA ;
Rosenquist, Å ;
Fenuik, W ;
Ellman, JA .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (09) :1817-1825
[42]   Designed molecules that fold to mimic protein secondary structures [J].
Stigers, KD ;
Soth, MJ ;
Nowick, JS .
CURRENT OPINION IN CHEMICAL BIOLOGY, 1999, 3 (06) :714-723
[43]   Template-constrained cyclic peptide analogues of somatostatin: Subtype-selective binding to somatostatin receptors and antiangiogenic activity [J].
Suich, DJ ;
Mousa, SA ;
Singh, G ;
Liapakis, G ;
Reisine, T ;
DeGrado, WF .
BIOORGANIC & MEDICINAL CHEMISTRY, 2000, 8 (09) :2229-2241
[44]   HIGHLY-ACTIVE CYCLIC AND BICYCLIC SOMATOSTATIN ANALOGS OF REDUCED RING SIZE [J].
VEBER, DF ;
HOLLY, FW ;
NUTT, RF ;
BERGSTRAND, SJ ;
BRADY, SF ;
HIRSCHMANN, R ;
GLITZER, MS ;
SAPERSTEIN, R .
NATURE, 1979, 280 (5722) :512-514
[45]  
Wang ZC, 1999, CHEM-EUR J, V5, P3273, DOI 10.1002/(SICI)1521-3765(19991105)5:11<3273::AID-CHEM3273>3.0.CO
[46]  
2-3
[47]  
Wuthrich K., 1986, NMR PROTEINS NUCL AC, DOI DOI 10.1051/EPN/19861701011