Retreatment using a dual mode of low-fluence Q-switched and long-pulse Nd:YAG laser in patients with melasma aggravation after previous therapy

被引:4
作者
Choi, Chun Pil [1 ]
Miyim, Seon [1 ]
Seo, Soo Hong [2 ]
Ahn, Hyo Hyun [2 ]
Kye, Young Chul [2 ]
Choi, Jae Eun [2 ]
机构
[1] Skyfeel Dermatol Clin, Seoul, South Korea
[2] Korea Univ, Coll Med, Dept Dermatol, Seoul 136705, South Korea
关键词
Adverse events; long-pulsed Nd:YAG laser; melasma; Q-switched Nd:YAG laser; rebound hyperpigmentation; ALUMINUM-GARNET LASER; 1,064 NM LASER; PUNCTATE LEUKODERMA; FACIAL MELASMA; ND/YAG LASER; 1064-NM; PHOTOTHERMOLYSIS; MELANOSOMES; LESIONS;
D O I
10.3109/14764172.2014.988730
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Background: Aggravated melasma after treatment is vulnerable to stimulation, can easily deteriorate, and may be distressing without proper management. Objective: To retrospectively assess the effectiveness and safety of combination therapy using low-fluence Q-switched neodymium-doped yttrium aluminum garnet (Nd:YAG) laser (QSNY) and long-pulse Nd:YAG laser (LPNY) (dual toning) in patients with rebound melasma. Materials and methods: A total of 30 patients with aggravated melasma after previous therapy who were treated with dual toning were enrolled. A total of 10 sessions were conducted at 1-week intervals, followed by maintenance treatment. The results were evaluated using the modified Melasma Area and Severity Index (mMASI) and the physician's global assessment (PGA) before and 2 months after completing the 10 treatment sessions. Results: The baseline mMASI was 10.48 +/- 3.64, which significantly decreased to 3.22 +/- 1.45 2 months after completing the 10 treatment sessions (p <0.001). Twenty-four patients (80%) had PGA grade 4 (76-100% improvement) and 6 patients (20%) had PGA grade 3 (51-75% improvement). Conclusion: Dual toning may be a safe and effective salvage treatment for patients with aggravated melasma after previous treatment. LPNY may stabilize melasma activity to prevent rebound hyperpigmentation via dermal remodeling.
引用
收藏
页码:129 / 134
页数:6
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