PRINS REACTION USING TRIOXANE FOR TRISUBSTITUTED,⁢ cis⁢-FUSED HEXAHYDRO-2⁢H⁢-FURO[3,2-⁢b⁢]PYRAN DERIVATIVE

被引：4

作者：

Hlokoane, Oriel ^{[1
]}

Itagaki, Hiyori ^{[1
]}

Chiba, Manami ^{[1
]}

Noda, Taiki ^{[1
]}

Takasaki, Yuichi ^{[1
]}

Miyako, Kei ^{[2
]}

Sakai, Ryuichi ^{[2
]}

Ishikawa, Yuichi ^{[1
]}

Oikawa, Masato ^{[1
]}

机构：

[1] Yokohama City Univ, Grad Sch Nanobiosci, Kanazawa Ku, Seto 22-2, Yokohama, Kanagawa 2360027, Japan

[2] Hokkaido Univ, Fac Fisheries Sci, Hakodate, Hokkaido 0418611, Japan

来源：

HETEROCYCLES | 2018年 / 96卷 / 03期

关键词：

D O I：

10.3987/COM-17-13776

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The construction of cis-fused heterobicyclic system involved in neuroactive natural products such as dysiherbaine has been accomplished by employing Prins strategy using 1,3,5-trioxane as an equivalent for formaldehyde. The reactions allowed stereoselective construction of the trisubstituted cis-fused hexahydro-2H-furo[3,2-b]pyran with maximum yield of 60%.

引用

页码：453 / 460

页数：8

共 14 条

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