The Comorbidity of ADHD and Bipolar Disorder: Any Less Confusion?

被引:17
作者
Pataki, Caroly [1 ]
Carlson, Gabrielle A. [2 ]
机构
[1] Univ So Calif, Keck Sch Med, Santa Monica, CA 90402 USA
[2] SUNY Stony Brook, Sch Med, Stony Brook, NY 11794 USA
关键词
ADHD; Pediatric bipolar disorder; Comorbidity; Childhood mania; Mood lability; ADHD and pediatric bipolar disorder; Manic/hypomanic episode; Childhood mood disorder; ADHD/bipolar treatment; Second generation antipsychotics; Comorbid ADHD and bipolar disorder; Childhood psychiatric diagnosis; Mood stabilizers; Impulsivity; Child psychiatry; DEFICIT HYPERACTIVITY DISORDER; ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; PLACEBO-CONTROLLED TRIAL; PROSPECTIVE FOLLOW-UP; DOUBLE-BLIND; I-DISORDER; PSYCHIATRIC-DISORDERS; MANIC SYMPTOMS; SPECTRUM DISORDER; DIVALPROEX SODIUM;
D O I
10.1007/s11920-013-0372-5
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
The clinical confusion surrounding childhood ADHD and bipolar disorder centers on overlaps between severe ADHD with mood lability and mania/hypomania. Perplexity has been exacerbated by the removal of mood symptoms from the diagnostic criteria for ADHD and a lack of stringent criteria for a manic/hypomanic episode. This review summarizes current knowledge of the relationship between ADHD and bipolar disorder, the rates with which ADHD and bipolar disorder coexist in youth of differing ages, their presence in community, clinical, and high risk samples, and their longitudinal course. Treatment studies are reviewed, highlighting findings in comorbid cases, which support the efficacy of stimulants and other agents for ADHD without worsening mood symptoms, and efficacy of second generation antipsychotics for bipolar disorder. In conclusion, a lack of clarity regarding the diagnostic boundaries between childhood ADHD and bipolar disorder remains, however, treatments targeting symptoms of each disorder when comorbid, provide some efficacy.
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页数:7
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