Message-Passing Algorithms for Sparse Network Alignment

被引:69
作者
Bayati, Mohsen [1 ]
Gleich, David F. [2 ]
Saberi, Amin [3 ]
Wang, Ying [4 ]
机构
[1] Stanford Univ, Grad Sch Business, Stanford, CA 94305 USA
[2] Purdue Univ, Dept Comp Sci, W Lafayette, IN 47907 USA
[3] Stanford Univ, Management Sci & Engn Dept, Stanford, CA 94305 USA
[4] Google, Mountain View, CA USA
基金
美国国家科学基金会;
关键词
Algorithms; Network alignment; graph matching; belief propagation; message-passing; PROTEIN-INTERACTION NETWORKS; GLOBAL ALIGNMENT; SIMILARITY;
D O I
10.1145/2435209.2435212
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
Network alignment generalizes and unifies several approaches for forming a matching or alignment between the vertices of two graphs. We study a mathematical programming framework for network alignment problem and a sparse variation of it where only a small number of matches between the vertices of the two graphs are possible. We propose a new message passing algorithm that allows us to compute, very efficiently, approximate solutions to the sparse network alignment problems with graph sizes as large as hundreds of thousands of vertices. We also provide extensive simulations comparing our algorithms with two of the best solvers for network alignment problems on two synthetic matching problems, two bioinformatics problems, and three large ontology alignment problems including a multilingual problem with a known labeled alignment.
引用
收藏
页数:31
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