In situdetection of intracellular tissue transglutaminase based on aggregation-induced emission

被引：6
作者：
Wu, Yafeng [1 ]
Gao, Yaqiong [1 ]
Su, Juan [1 ]
Chen, Zixuan [1 ]
Liu, Songqin [1 ]
机构：
[1] Southeast Univ, Jiangsu Engn Lab Smart Carbon Rich Mat & Device, Sch Chem & Chem Engn, Nanjing 211189, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2020年 / 56卷 / 63期
基金：
中国国家自然科学基金;
关键词：
CANCER CELLS; PROTEIN; QUANTIFICATION; APOPTOSIS; PROBE;
D O I：
10.1039/d0cc03365k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Herein, a novel strategy forin situimaging and real-time monitoring of intracellular tissue transglutaminase (TG2) is presented based on aggregation-induced emission (AIE). It has high sensitivity and specificity, minimal background signal and can also effectively distinguish different cell types (drug-resistant cancer cells, cancer cells and normal cells).
引用
收藏
页码：9008 / 9011
页数：4
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