New guaiane and acorane sesquiterpenes in high quality agarwood "Qi-Nan" from Aquilaria sinensis

被引：23

作者：

Yang, Delan ^{[1
]}

Wang, Jun ^{[1
]}

Li, Wei ^{[1
]}

Dong, Wenhua ^{[1
]}

Mei, Wenli ^{[1
]}

Dai, Haofu ^{[1
]}

机构：

[1] Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Key Lab Biol & Genet Resources Trop Crops, Minist Agr, Haikou 571101, Peoples R China

来源：

PHYTOCHEMISTRY LETTERS | 2016年 / 17卷

关键词：

Agarwood; Aquilaria sinensis; Qi-Nan; Guaianes; Acoranes; Fagrant sesquiterpene; AChE inhibitory activities; CONSTITUENTS; DERIVATIVES; CHROMONE;

D O I：

10.1016/j.phytol.2016.07.017

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new guaiane sesquiterpenes (1-2), one new acorane sesquiterpene (3), along with two known sesquiterpenes (4-5) were isolated from high quality agarwood 'Qi-Nan' originating from Aquilaria sinensis. Their structures were established based on spectroscopic methods including IR, HRESIMS, 1D, and 2D NMR. Compound 1 was a guaiane sesquiterpene lactone, and compound 2 was a guaiane sesquiterpene with a 5/6/7 ring carbon skeleton. Compounds 3 and 4 were acorane-type sesquiterpenes. The two acorane sesquiterpenes (3-4) possess lasting fragrant smell at room temperature. These isolated guaiane and acorane sesquiterpenes showed acetylcholinesterase inhibitory activities in different degrees ranged from 19% to 44% at the concentration of 50 mg/mL. (C) 2016 Phytochemical Society of Europe. Published by Elsevier Ltd. All rights reserved.

引用

页码：94 / 99

页数：6

共 19 条

[1]

[Anonymous], EUR J ORG CHEM

[2]

Barden A., 2000, Heart of the matter: agarwood use and trade and CITES implementation for Aquilaria malaccensis, P1

[3] A NEW AND RAPID COLORIMETRIC DETERMINATION OF ACETYLCHOLINESTERASE ACTIVITY [J].