Anticoagulation in Pregnancy

被引：45
作者：
Goland, Sorel [1 ]
Elkayam, Uri [2 ]
机构：
[1] Kaplan Med Ctr, Dept Cardiol, IL-76100 Rehovot, Israel
[2] Univ So Calif, Dept Med, Div Cardiovasc Dis, Los Angeles, CA 90033 USA
来源：
CARDIOLOGY CLINICS | 2012年 / 30卷 / 03期
关键词：
Pregnancy; Anticoagulation; Mechanical prosthetic valves; Thromboembolism; Antithrombotic therapy; MOLECULAR-WEIGHT HEPARIN; MECHANICAL HEART-VALVES; PERIPARTUM CARDIOMYOPATHY; VENOUS THROMBOEMBOLISM; PULMONARY-EMBOLISM; HEMOSTATIC CHANGES; RISK-FACTORS; WOMEN; WARFARIN; DISEASE;
D O I：
10.1016/j.ccl.2012.05.003
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Pregnancy-associated thrombosis is an important cause of morbidity and mortality during pregnancy. Anticoagulation therapy is an important component of the management of thrombotic complications in pregnancy but may result in fetal and maternal complications. Although evidence-based recommendations are available for the prevention and treatment of venous thromboembolism, the management of pregnant women with mechanical valves still presents a challenge, because there are no controlled clinical trials to provide guidelines for optimal antithrombotic therapy. This review presents information on anticoagulation therapy during pregnancy for thromboembolic prophylaxis in women with various cardiovascular disorders, focusing on patients with mechanical heart valves.
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收藏
页码：395 / +
页数：12
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