Chromolithic Method Development, Validation and System Suitability Analysis of Ultra-Sound Assisted Extraction of Glycyrrhizic Acid and Glycyrrhetinic Acid from Glycyrrhiza glabra

被引：0

作者：

Gupta, Suphla ^{[2
]}

Sharma, Rajni ^{[3
]}

Pandotra, Pankaj ^{[2
]}

Jaglan, Sundeep ^{[2
]}

Gupta, Ajai Prakash ^{[1
]}

机构：

[1] Indian Inst Integrat Med, Patent Cell Div, Jammu 180001, Jammu & Kashmir, India

[2] Indian Inst Integrat Med, Plant Biotechnol Div, Jammu 180001, Jammu & Kashmir, India

[3] Indian Inst Integrat Med, Nat Prod Div, Jammu 180001, Jammu & Kashmir, India

来源：

NATURAL PRODUCT COMMUNICATIONS | 2012年 / 7卷 / 08期

关键词：

Chromolith-100; Glycyrrhizic acid; Glycyrrhetinic acid; Glycyrrhiza glabra; Root; LIQUID-CHROMATOGRAPHIC DETERMINATION; 18-BETA-GLYCYRRHETINIC ACID; LICORICE ROOTS; HUMAN-PLASMA; PERFORMANCE; SILICA;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

An ultrasound-assisted extraction and chromolithic LC method was developed for simultaneous determination of glycyrrhizic acid (GA) and glycyrrhetinic acid (GL) from the root extract of Glycyrrhiza glabra using RPLC-PDA. The developed method was validated according to the International Conference on Harmonisation. The method exhibited good linearity (r(2)>0.9989) with high precision and achieved good accuracies between 97.5 to 101.3% of quantitative results. The method is more sensitive and faster (resolved within ten minutes) than the earlier developed methods using normal LC columns.

引用

页码：991 / 994

页数：4

共 31 条

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