Chromolithic Method Development, Validation and System Suitability Analysis of Ultra-Sound Assisted Extraction of Glycyrrhizic Acid and Glycyrrhetinic Acid from Glycyrrhiza glabra

被引：0
|
作者：
Gupta, Suphla [2 ]
Sharma, Rajni [3 ]
Pandotra, Pankaj [2 ]
Jaglan, Sundeep [2 ]
Gupta, Ajai Prakash [1 ]
机构：
[1] Indian Inst Integrat Med, Patent Cell Div, Jammu 180001, Jammu & Kashmir, India
[2] Indian Inst Integrat Med, Plant Biotechnol Div, Jammu 180001, Jammu & Kashmir, India
[3] Indian Inst Integrat Med, Nat Prod Div, Jammu 180001, Jammu & Kashmir, India
来源：
NATURAL PRODUCT COMMUNICATIONS | 2012年 / 7卷 / 08期
关键词：
Chromolith-100; Glycyrrhizic acid; Glycyrrhetinic acid; Glycyrrhiza glabra; Root; LIQUID-CHROMATOGRAPHIC DETERMINATION; 18-BETA-GLYCYRRHETINIC ACID; LICORICE ROOTS; HUMAN-PLASMA; PERFORMANCE; SILICA;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
An ultrasound-assisted extraction and chromolithic LC method was developed for simultaneous determination of glycyrrhizic acid (GA) and glycyrrhetinic acid (GL) from the root extract of Glycyrrhiza glabra using RPLC-PDA. The developed method was validated according to the International Conference on Harmonisation. The method exhibited good linearity (r(2)>0.9989) with high precision and achieved good accuracies between 97.5 to 101.3% of quantitative results. The method is more sensitive and faster (resolved within ten minutes) than the earlier developed methods using normal LC columns.
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收藏
页码：991 / 994
页数：4
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