Association of Self-Reported Medication Adherence with Potentially Inappropriate Medications in Elderly Patients: A Cross-Sectional Pilot Study

被引：8

作者：

Miyazaki, Motoyasu ^{[1
,2
]}

Uchiyama, Masanobu ^{[2
]}

Nakamura, Yoshihiko ^{[3
]}

Matsuo, Koichi ^{[1
,2
]}

Ono, Chika ^{[2
,4
]}

Goto, Miwa ^{[2
]}

Unoki, Ayako ^{[2
]}

Nakashima, Akio ^{[1
,2
]}

Imakyure, Osamu ^{[1
,2
]}

机构：

[1] Fukuoka Univ, Fac Pharmaceut Sci, Dept Pharmaceut & Hlth Care Management, Fukuoka 8140180, Japan

[2] Fukuoka Univ, Dept Pharm, Chikushino 8188502, Japan

[3] Fukuoka Univ, Fac Med, Dept Emergency & Crit Care Med, Fukuoka 8140180, Japan

[4] Oita Nakamura Hosp, Dept Pharm, Oita 8700022, Japan

来源：

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH | 2020年 / 17卷 / 16期

关键词：

elderly patients; polypharmacy; potentially inappropriate medication; self-reported medication adherence; visual analogue scale; ADVERSE DRUG-REACTIONS; PERSONS APPROPRIATE PRESCRIPTIONS; VISUAL ANALOG SCALE; OLDER-PEOPLE; SCREENING TOOL; POLYPHARMACY; RISK; CRITERIA; OUTCOMES; NONADHERENCE;

D O I：

10.3390/ijerph17165940

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Background: Polypharmacy (PP) and potentially inappropriate medications (PIMs) cause problematic drug-related issues in elderly patients; however, little is known about the association between medication adherence and PP and PIMs. This study evaluated the association of self-reported medication adherence with PP and PIMs in elderly patients. Methods: A cross-sectional pilot study was conducted using data collected from electronic medical records of 142 self-administering patients aged >= 65 years, excluding emergency hospitalization cases. Self-reported medication adherence was assessed using the visual analogue scale (VAS). Results: Of the 142 patients, 91 (64.1%) had PP and 80 (56.3%) used at least one PIM. In univariate analysis, patients with a VAS score of 100% had a significantly higher number of female patients and >= 1 PIM use compared to other patients. We found no association between the VAS score and PP. In multivariable analysis, the use of PIMs was significantly associated with a VAS score of 100% (odds ratio = 2.32; 95% confidence interval = 1.16-4.72;p= 0.017). Conclusions: Use of PIMs by elderly patients is significantly associated with self-reported medication adherence. Pharmacists should pay more attention to prescribed medications of self-administering elderly patients in order to improve their prescribing quality.

引用

页码：1 / 13

页数：13