Absolute Configuration and 1H NMR Characterization of Rosmaridiphenol Diacetate

被引：21

作者：

Munoz, Marcelo A. ^{[2
]}

Perez-Hernandez, Nury ^{[3
]}

Pertino, Mariano W. ^{[4
]}

Schmeda-Hirschmann, Guillermo ^{[4
]}

Joseph-Nathan, Pedro ^{[1
]}

机构：

[1] Inst Politecn Nacl, Ctr Invest & Estudios Avanzados, Dept Quim, Mexico City 07000, DF, Mexico

[2] Univ Austral Chile, Fac Ciencias, Inst Ciencias Quim, Valdivia, Chile

[3] Inst Politecn Nacl, Escuela Nacl Med & Homeopatia, Programa Inst Biomed Mol, Mexico City 07320, DF, Mexico

[4] Univ Talca, Inst Quim Recursos Nat, Talca, Chile

来源：

JOURNAL OF NATURAL PRODUCTS | 2012年 / 75卷 / 04期

关键词：

SPECTRAL-ANALYSIS;

D O I：

10.1021/np200951y

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The correction of patented structure 1 of rosmaridiphenol, an antioxidant isolated from rosemary, Rosmarinus officinalis, was made recently. The correct structure is proposed as 11,12-dihydroxy-8,11,13-icetexatrien-l-one (2a) based on 2D NMR data. In order to further support the structure, this work reports the single-crystal X-ray analysis, the complete H-1 NMR assignment by full spin-spin simulation, and the absolute configuration of the diacetate 2b derived via vibrational circular dicroism measurements in comparison with density functional theory calculated data.

引用

页码：779 / 783

页数：5

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