Targeting IDH: the next big thing in AML

被引：16

作者：

Levis, Mark ^{[1
]}

机构：

[1] Johns Hopkins Univ, Baltimore, MD 21218 USA

来源：

BLOOD | 2013年 / 122卷 / 16期

关键词：

MUTATIONS;

D O I：

10.1182/blood-2013-09-522441

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In this issue of Blood, Chaturvedi and coworkers use a small molecule inhibitor of mutant isocitrate dehydrogenase 1 (IDH1) to reverse the myeloproliferative effects induced by the oncometabolite" 2-hydroxyglutarate (2-HG). © 2013 by The American Society of Hematology."

引用

页码：2770 / 2771

页数：4

共 8 条

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