Synthesis of nitrodienes, nitrostyrenes, and nitrobiaryls through palladium-catalyzed couplings of β-nitrovinyl and o-nitroaryl thioethers

被引：27

作者：

Creech, Gardner S. ^{[1
]}

Kwon, Ohyun ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA

来源：

CHEMICAL SCIENCE | 2013年 / 4卷 / 06期

基金：

美国国家科学基金会;

关键词：

CONJUGATE ADDITION; STEREOSELECTIVE-SYNTHESIS; REDUCTIVE CYCLIZATION; GENERAL-SYNTHESIS; ETHYL PHOSPHITES; NOBEL LECTURE; EFFICIENT; OLEFINS; REAGENTS; CARBAZOLES;

D O I：

10.1039/c3sc50773d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A highly efficient, base-free, mild protocol for the palladium-catalyzed, copper-activated desulfitative couplings of vinyl and aryl beta-nitrothioethers generates a wide variety of conjugated nitroorganics. Orthogonality to traditional Suzuki-Miyaura coupling is demonstrated, as well as synthetic utility, through reductive Cadogan cyclization, for the formation of indoles, carbazoles, and pyrroles.

引用

页码：2670 / 2674

页数：5

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