A Mild and Green Method for the N-BOC Protection of Amines without Assistant of Catalyst Under Solvent-free Conditions

被引：0
|
作者：
Mojtahedi, Mohammad Majid [1 ]
Niknejad, Nina [2 ]
Veisi, Hojat [3 ]
机构：
[1] Chem & Chem Engn Res Ctr Iran, Tehran, Iran
[2] Islamic Azad Univ, Borujerd Branch, Dept Chem, Borujerd, Iran
[3] Payame Noor Univ, Dept Chem, Tehran 193954697, Iran
来源：
LETTERS IN ORGANIC CHEMISTRY | 2013年 / 10卷 / 02期
关键词：
N-BOC protection; green; catalyst-free; solvent-free; TERT-BUTYL DICARBONATE; ONE-POT SYNTHESIS; HIGHLY EFFICIENT; BUTOXYCARBONYLATION; ACID; DEPROTECTION; SILICA; AMIDES;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A facile, green and versatile method for the Boc protection of amines has been developed by a treatment with (Boc)(2)O without any additive at room temperature. The method is general for the preparation of N-Boc derivatives of aliphatic (acyclic and cyclic), aromatic, and heteroaromatic amines; primary and secondary amines. The advantages of this method are green, simplicity, short reaction times and excellent yields.
引用
收藏
页码：121 / 125
页数：5
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