A Mild and Green Method for the N-BOC Protection of Amines without Assistant of Catalyst Under Solvent-free Conditions

被引：0
|
作者：
Mojtahedi, Mohammad Majid [1 ]
Niknejad, Nina [2 ]
Veisi, Hojat [3 ]
机构：
[1] Chem & Chem Engn Res Ctr Iran, Tehran, Iran
[2] Islamic Azad Univ, Borujerd Branch, Dept Chem, Borujerd, Iran
[3] Payame Noor Univ, Dept Chem, Tehran 193954697, Iran
来源：
LETTERS IN ORGANIC CHEMISTRY | 2013年 / 10卷 / 02期
关键词：
N-BOC protection; green; catalyst-free; solvent-free; TERT-BUTYL DICARBONATE; ONE-POT SYNTHESIS; HIGHLY EFFICIENT; BUTOXYCARBONYLATION; ACID; DEPROTECTION; SILICA; AMIDES;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A facile, green and versatile method for the Boc protection of amines has been developed by a treatment with (Boc)(2)O without any additive at room temperature. The method is general for the preparation of N-Boc derivatives of aliphatic (acyclic and cyclic), aromatic, and heteroaromatic amines; primary and secondary amines. The advantages of this method are green, simplicity, short reaction times and excellent yields.
引用
收藏
页码：121 / 125
页数：5
相关论文
共 50 条
  • [1] Malic Acid as a Green Catalyst for the N-Boc Protection under Solvent-free Condition
    Pise, Ashok
    Patil, Shripad M.
    Ingale, Ajit P.
    LETTERS IN ORGANIC CHEMISTRY, 2024, 21 (07) : 620 - 629
  • [2] Poly(N-vinylimidazole) as a halogen-free and efficient catalyst for N-Boc protection of amines under solvent-free conditions
    Khaligh, Nader Ghaffari
    RSC ADVANCES, 2012, 2 (32): : 12364 - 12370
  • [3] Introduction of a Tropine-based Dicationic Catalyst for the N-Boc Protection and Acetylation of Amines under Solvent-free Conditions
    Pourdasht, S.
    Mousapour, M.
    Shirini, F.
    Tajik, H.
    ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL, 2024, 56 (04) : 392 - 401
  • [4] Environmentally benign N-Boc protection under solvent- and catalyst-free conditions
    Jia, Xueshun
    Huang, Qing
    Li, Jian
    Li, Shaoyu
    Yang, Qiushi
    SYNLETT, 2007, (05) : 806 - 808
  • [5] Nanocrystalline TiO2-HClO4:A novel,efficient and recyclable catalyst for the chemoselective N-Boc protection of amines under solvent-free conditions
    Farhad Shirini
    Seyyed Vahid Atghia
    Mojtaba Ghazi Jirdehi
    Chinese Chemical Letters, 2013, 24 (01) : 34 - 36
  • [6] Nanocrystalline TiO2-HClO4: A novel, efficient and recyclable catalyst for the chemoselective N-Boc protection of amines under solvent-free conditions
    Shirini, Farhad
    Atghia, Seyyed Vahid
    Jirdehi, Mojtaba Ghazi
    CHINESE CHEMICAL LETTERS, 2013, 24 (01) : 34 - 36
  • [7] A simple, rapid, and efficient N-Boc protection of amines under ultrasound irradiation and catalyst-free conditions
    Amira, Aicha
    K'tir, Hacene
    Berredjem, Malika
    Aouf, Nour-Eddine
    MONATSHEFTE FUR CHEMIE, 2014, 145 (03): : 509 - 515
  • [8] A simple, rapid, and efficient N-Boc protection of amines under ultrasound irradiation and catalyst-free conditions
    Aïcha Amira
    Hacène K’tir
    Malika Berredjem
    Nour-Eddine Aouf
    Monatshefte für Chemie - Chemical Monthly, 2014, 145 : 509 - 515
  • [9] Efficient and expeditious chemoselective BOC protection of amines in catalyst and solvent-free media
    Balaga Viswanadham
    Abdul S. Mahomed
    Holger B. Friedrich
    Sooboo Singh
    Research on Chemical Intermediates, 2017, 43 : 1355 - 1363
  • [10] Efficient and expeditious chemoselective BOC protection of amines in catalyst and solvent-free media
    Viswanadham, Balaga
    Mahomed, Abdul S.
    Friedrich, Holger B.
    Singh, Sooboo
    RESEARCH ON CHEMICAL INTERMEDIATES, 2017, 43 (03) : 1355 - 1363
12345