Alternative splicing and genome complexity

被引：369

作者：

Brett, D

Pospisil, H

Valcárcel, J

Reich, J

Bork, P

机构：

[1] Max Delbruck Ctr Mol Med, D-13125 Berlin, Germany

[2] European Mol Biol Lab, D-69012 Heidelberg, Germany

来源：

NATURE GENETICS | 2002年 / 30卷 / 01期

关键词：

D O I：

10.1038/ng803

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Alternative splicing of mRNA allows many gene products with different functions to be produced from a single coding sequence. It has recently been proposed as a mechanism by which higher-order diversity is generated. Here we show, using large-scale expressed sequence tag (EST) analysis, that among seven different eukaryotes the amount of alternative splicing is comparable, with no large differences between humans and other animals.

引用

页码：29 / 30

页数：2

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