The OpenGATE ecosystem for Monte Carlo simulation in medical physics

被引:52
作者
Sarrut, David [1 ,2 ,3 ,4 ,5 ,6 ]
Arbor, Nicolas [7 ]
Baudier, Thomas [1 ,2 ,3 ,4 ,5 ,6 ]
Borys, Damian [8 ]
Etxebeste, Ane [1 ,2 ,3 ,4 ,5 ,6 ]
Fuchs, Hermann [9 ,10 ]
Gajewski, Jan [11 ]
Grevillot, Loiec [9 ]
Jan, Sebastien [12 ]
Kagadis, George C. [13 ]
Kang, Han Gyu [14 ]
Kirov, Assen [15 ]
Kochebina, Olga [12 ]
Krzemien, Wojciech [16 ,17 ,18 ]
Lomax, Antony [19 ,20 ]
Papadimitroulas, Panagiotis [21 ]
Pommranz, Christian [22 ,23 ]
Roncali, Emilie [24 ,25 ]
Rucinski, Antoni [11 ]
Winterhalter, Carla [19 ,20 ]
Maigne, Lydia [26 ]
机构
[1] Univ Lyon, Lyon, France
[2] CREATIS, Lyon, France
[3] CNRS, UMR5220, Lyon, France
[4] INSERM, U1294, Lyon, France
[5] INSA Lyon, Lyon, France
[6] Univ Lyon 1, Leon Berard Canc Ctr, Lyon, France
[7] Univ Strasbourg, CNRS, IPHC, F-67037 Strasbourg, France
[8] Silesian Tech Univ, Dept Syst Biol & Engn, Gliwice, Poland
[9] MedAustron Ion Therapy Ctr, Wiener Neustadt, Austria
[10] Med Univ Vienna, Dept Radiat Oncol, Wahringer Gurtel 18-20, A-1090 Vienna, Austria
[11] Polish Acad Sci, Inst Nucl Phys, Krakow, Poland
[12] Univ Paris Saclay, CNRS, INSERM, Lab Imagerie Biomed Multimodale BioMaps,CEA, F-91401 Orsay, France
[13] Univ Patras, Sch Med, Dept Med Phys, 3DMI Res Grp, Patras, Greece
[14] Natl Inst Quantum Sci & Technol QST, Inage Ku, 4-9-1 Anagawa, Chiba 2638555, Japan
[15] Mem Sloan Kettering Canc, New York, NY 10021 USA
[16] Natl Ctr Nucl Res, High Energy Phys Div, Otwock, Poland
[17] Jagiellonian Univ, Fac Phys Astron & Appl Comp Sci, S Lojasiewicza 11, PL-30348 Krakow, Poland
[18] Jagiellonian Univ, Ctr Theranost, Kopernika 40 St, PL-31501 Krakow, Poland
[19] PSI, Ctr Proton Therapy, Villigen, Switzerland
[20] Swiss Fed Inst Technol, Dept Phys, Zurich, Switzerland
[21] BIOEMTECH, Bioemiss Technol Solut IKE, Athens, Greece
[22] Eberhard Karls Univ Tuebingen, Dept Preclin Imaging & Radiopharm, Werner Siemens Imaging Ctr, Roentgenweg 13, D-72076 Tubingen, Germany
[23] Eberhard Karls Univ Tuebingen, Inst Astron & Astrophys, Sand 1, D-72076 Tubingen, Germany
[24] Univ Calif Davis, Dept Biomed Engn, Davis, CA 95616 USA
[25] Univ Calif Davis, Dept Radiol, Davis, CA 95616 USA
[26] Univ Clermont Auvergne, CNRS, UMR 6533, Lab Phys Clermont, F-63178 Aubiere, France
关键词
Monte Carlo; Gate; Geant4; simulation; C PLUS PLUS; PROTON THERAPY; X-RAY; SECONDARY PARTICLES; RADIATION BIOLOGY; DOSE ENHANCEMENT; BRAIN NECROSIS; GATE; MODEL; PET;
D O I
10.1088/1361-6560/ac8c83
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
This paper reviews the ecosystem of GATE, an open-source Monte Carlo toolkit for medical physics. Based on the shoulders of Geant4, the principal modules (geometry, physics, scorers) are described with brief descriptions of some key concepts (Volume, Actors, Digitizer). The main source code repositories are detailed together with the automated compilation and tests processes (Continuous Integration). We then described how the OpenGATE collaboration managed the collaborative development of about one hundred developers during almost 20 years. The impact of GATE on medical physics and cancer research is then summarized, and examples of a few key applications are given. Finally, future development perspectives are indicated.
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页数:18
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